Tuberculosis in children.

Tuberculosis (TB) control poses one of the major global health challenges in the new millennium. Children in TB-endemic areas suffer severe TB related morbidity and mortality, despite the availability of cheap and effective TB treatment. However, providing an accurate TB diagnosis together with access to supervised, child friendly treatment remains difficult in resource-limited settings. This review provides a broad overview of recent advances related to child TB, focusing on intra-thoracic disease manifestations. It summarizes current understanding of TB epidemiology, disease prevention, diagnosis and treatment, but also introduces novel concepts for further discussion and future evaluation.