Literature DB >> 18305999

Propofol decreases early postoperative nausea and vomiting in patients undergoing thyroid and parathyroid operations.

Paul G Gauger1, Amy Shanks, Michelle Morris, Mary Lou V H Greenfield, Richard E Burney, Michael O'Reilly.   

Abstract

BACKGROUND: As the practice of parathyroid and thyroid surgery shifts toward short stay and outpatient treatment, the occurrence and management of postoperative nausea and vomiting (PONV) increases in importance due to its potential to delay discharge. PONV also may contribute negatively to the patient's experience and thus their level of satisfaction. The purpose of this study was to determine whether anesthetic technique based on propofol decreases the incidence of PONV and, consequently, improves patient satisfaction with their care.
METHODS: A prospective, randomized trial included patients undergoing thyroidectomy and parathyroidectomy under general anesthetic with (75 patients) or without (73 patients) propofol. Occurrences of nausea, vomiting, and the resultant treatment were tracked during the perioperative period. Repeated questionnaires at multiple time points determined patient expectations and experiences related to PONV after their operation. Statistical analyses compared differences between the propofol and non-propofol groups.
RESULTS: PONV was significantly less likely in the propofol group at the early time points (in the operating room and postanesthesia care unit) but not at later time points (postoperative day 1 or 2). Patients were largely satisfied with different aspects of their management despite the specifics of their anesthetic regimen.
CONCLUSIONS: A propofol-based anesthetic decreases PONV immediately after the operation but this influence does not persist throughout the episode of care or significantly contribute to patient perceptions of satisfaction.

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Year:  2008        PMID: 18305999     DOI: 10.1007/s00268-008-9472-5

Source DB:  PubMed          Journal:  World J Surg        ISSN: 0364-2313            Impact factor:   3.352


  18 in total

1.  The use of propofol for its antiemetic effect: a survey of clinical practice in the United States.

Authors:  A J Soppitt; P S Glass; S Howell; K Weatherwax; T J Gan
Journal:  J Clin Anesth       Date:  2000-06       Impact factor: 9.452

2.  Recovery profile, costs, and patient satisfaction with propofol and sevoflurane for fast-track office-based anesthesia.

Authors:  J Tang; L Chen; P F White; M F Watcha; R H Wender; R Naruse; R Kariger; A Sloninsky
Journal:  Anesthesiology       Date:  1999-07       Impact factor: 7.892

3.  Comparison of vital capacity induction with sevoflurane to intravenous induction with propofol for adult ambulatory anesthesia.

Authors:  B K Philip; L L Lombard; E R Roaf; L R Drager; I Calalang; J H Philip
Journal:  Anesth Analg       Date:  1999-09       Impact factor: 5.108

4.  Reversal of neuromuscular blockade with neostigmine has no effect on the incidence or severity of postoperative nausea and vomiting.

Authors:  J Hovorka; K Korttila; K Nelskylä; A Soikkeli; J Sarvela; H Paatero; P Halonen; A Yli-Hankala
Journal:  Anesth Analg       Date:  1997-12       Impact factor: 5.108

5.  Sevoflurane versus propofol for anesthetic induction: a meta-analysis.

Authors:  H S Joo; W J Perks
Journal:  Anesth Analg       Date:  2000-07       Impact factor: 5.108

6.  Cost comparison: a desflurane- versus a propofol-based general anesthetic technique.

Authors:  M K Rosenberg; P Bridge; M Brown
Journal:  Anesth Analg       Date:  1994-11       Impact factor: 5.108

7.  Propofol maintenance to reduce postoperative emesis in thyroidectomy patients: a group sequential comparison with isoflurane/nitrous oxide.

Authors:  C D Brooker; J Sutherland; M J Cousins
Journal:  Anaesth Intensive Care       Date:  1998-12       Impact factor: 1.669

8.  Lack of efficacy of propofol in the treatment of early postoperative nausea and vomiting.

Authors:  I Harper; E Della-Marta; H Owen; J Plummer; A Ilsley
Journal:  Anaesth Intensive Care       Date:  1998-08       Impact factor: 1.669

9.  Treatment of postoperative nausea and vomiting after outpatient surgery with the 5-HT3 antagonist ondansetron.

Authors:  P Scuderi; B Wetchler; Y F Sung; M Mingus; S DuPen; L Claybon; J Leslie; P Talke; J Apfelbaum; S Sharifi-Azad
Journal:  Anesthesiology       Date:  1993-01       Impact factor: 7.892

10.  Outpatient thyroid and parathyroid surgery: a prospective study of feasibility, safety, and costs.

Authors:  P M Mowschenson; R A Hodin
Journal:  Surgery       Date:  1995-12       Impact factor: 3.982

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  8 in total

1.  Postoperative nausea and vomiting after endoscopic thyroidectomy: total intravenous vs. balanced anesthesia.

Authors:  Gunn Hee Kim; Hyun Joo Ahn; Hyun-Soo Kim; Si Ra Bang; Hyun-Sung Cho; Mikyung Yang; Jie Ae Kim
Journal:  Korean J Anesthesiol       Date:  2011-06-17

Review 2.  Intravenous versus inhalational maintenance of anaesthesia for postoperative cognitive outcomes in elderly people undergoing non-cardiac surgery.

Authors:  David Miller; Sharon R Lewis; Michael W Pritchard; Oliver J Schofield-Robinson; Cliff L Shelton; Phil Alderson; Andrew F Smith
Journal:  Cochrane Database Syst Rev       Date:  2018-08-21

3.  Effects of Systemic Lidocaine Versus Dexmedetomidine on the Recovery Quality and Analgesia After Thyroid Cancer Surgery: A Randomized Controlled Trial.

Authors:  Teng Shu; Siqi Xu; Xia Ju; Shenghong Hu; Shengbin Wang; Li Ma
Journal:  Pain Ther       Date:  2022-10-06

4.  Clinical Efficacy of Intravenous Lidocaine for Thyroidectomy: A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial.

Authors:  Geun Joo Choi; Hyun Kang; Eun Jin Ahn; Jong In Oh; Chong Wha Baek; Yong Hun Jung; Jin Yun Kim
Journal:  World J Surg       Date:  2016-12       Impact factor: 3.352

5.  Effects of remifentanil versus nitrous oxide on postoperative nausea, vomiting, and pain in patients receiving thyroidectomy: Propensity score matching analysis.

Authors:  Min Kyoung Kim; Myung Sub Yi; Hyun Kang; Geun-Joo Choi
Journal:  Medicine (Baltimore)       Date:  2016-10       Impact factor: 1.889

6.  Incidence of postoperative nausea and vomiting is not increased by combination of low concentration sevoflurane and propofol compared with propofol alone in patients undergoing laparoscopic gynecological surgery.

Authors:  Yuka Uchinami; Satoshi Takikawa; Fumiki Takashima; Yosuke Maeda; Satoki Nasu; Ayumi Ito; Tatushi Saito
Journal:  JA Clin Rep       Date:  2019-11-02

7.  Effect of total intravenous anaesthesia and prophylactic ramosetron on postoperative nausea and vomiting after thyroidectomy: A prospective, randomized controlled study.

Authors:  Han Bum Joe; Sook Young Lee; Jin-Soo Kim; Hyuk Soo Chang; Yunyong Jeong; Haewon Jeong; Sung Yong Park
Journal:  J Int Med Res       Date:  2015-12-10       Impact factor: 1.671

8.  Efficacy of Intravenous Paracetamol in Combination with Lidocaine Pretreatment for Reducing Pain During Injection of Propofol.

Authors:  Muhammad Hayat; Gauhar Afshan; Muhammad Nasir; Samie Asghar; Abdul Monem
Journal:  Cureus       Date:  2020-02-09
  8 in total

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