| Literature DB >> 18304700 |
E Gomard-Mennesson1, P Sève, E De La Roche, S Collardeau-Frachon, C Lombard-Bohas, C Broussolle.
Abstract
Ectopic adrenocorticotropic (ACTH) syndrome is a rare condition, generally due to lung or carcinoid tumors. 18-fluorodeoxy-glucose positron emission tomography ((18)FDG-PET) can be useful where conventional localization techniques often fail. A 50-year-old man presented with sudden diffuse oedema, hypokaliemic alkalosis, Diabetes mellitus and high serum levels of ACTH and cortisol. Ectopic ACTH syndrome was confirmed leading to ketoconazole treatment. Chest-computed tomography only revealed an aspecific anterior mediastinal nodule that was hypermetabolic on the whole body-(18)FDG-PET. A thymic tumor was suspected and the patient had a thymectomy that revealed an atypical carcinoid tumor with pleural carcinosis. The postoperative course was favorable with clinical and biochemical remission of neoplastic Cushing's syndrome.Entities:
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Year: 2008 PMID： 18304700 DOI： 10.1016/j.revmed.2008.01.007
Source DB: PubMed Journal: Rev Med Interne ISSN： 0248-8663 Impact factor: 0.728