PURPOSE OF REVIEW: Researchers have recently sought out pharmacologic means of increasing rates of urinary stone passage. We outline the current understanding in medical expulsive therapy. RECENT FINDINGS: We review available articles characterizing pharmaceutical agents including alpha receptor antagonists as medical expulsive agents. SUMMARY: Medical expulsive therapy for ureteral stones provides a nonsurgical option for patients with ureteral stones. In view of the available clinical trials and meta-analysis, patients with distal ureteral stones measuring less than 1 cm who are candidates for observation warrant a trial of medical expulsive therapy.
PURPOSE OF REVIEW: Researchers have recently sought out pharmacologic means of increasing rates of urinary stone passage. We outline the current understanding in medical expulsive therapy. RECENT FINDINGS: We review available articles characterizing pharmaceutical agents including alpha receptor antagonists as medical expulsive agents. SUMMARY: Medical expulsive therapy for ureteral stones provides a nonsurgical option for patients with ureteral stones. In view of the available clinical trials and meta-analysis, patients with distal ureteral stones measuring less than 1 cm who are candidates for observation warrant a trial of medical expulsive therapy.
Authors: Barbrina Dunmire; Franklin C Lee; Ryan S Hsi; Bryan W Cunitz; Marla Paun; Michael R Bailey; Mathew D Sorensen; Jonathan D Harper Journal: J Endourol Date: 2014-09-17 Impact factor: 2.942
Authors: Barbrina Dunmire; Jonathan D Harper; Bryan W Cunitz; Franklin C Lee; Ryan Hsi; Ziyue Liu; Michael R Bailey; Mathew D Sorensen Journal: J Urol Date: 2015-08-22 Impact factor: 7.450
Authors: Jonathan D Harper; Bryan W Cunitz; Barbrina Dunmire; Franklin C Lee; Mathew D Sorensen; Ryan S Hsi; Jeff Thiel; Hunter Wessells; James E Lingeman; Michael R Bailey Journal: J Urol Date: 2015-10-30 Impact factor: 7.450