Literature DB >> 18301298

Validation of the reflux disease questionnaire for an Italian population of patients with gastroesophageal reflux disease.

Fabio Pace1, Pamela Scarlata, Valentina Casini, Piercarlo Sarzi-Puttini, Gabriele Bianchi Porro.   

Abstract

BACKGROUND/AIMS: The reflux disease questionnaire (RDQ) is a very simple questionnaire based on only 12 questions that can be answered and evaluated quickly in a primary care setting, which was already found to be valid and reliable in the diagnosis of gastroesophageal reflux disease (GERD). As an English and a German version of the RDQ exist, but not an Italian one, we aimed at translating the RDQ into Italian and evaluating its reliability for the use of Italian-speaking GERD patients. PATIENTS/
METHODS: For the purpose of linguistic validation, we translated backward and forward the original RDQ into Italian and again into English. For the purpose of assessing internal consistency, test-retest, and interrater reliability, 130 GERD patients were used, of whom 57 patients had an endoscopic oesophagitis of grade A to C according to the Los Angeles classification and 63 patients had uninvestigated GERD symptoms but with a frequency of heartburn and/or regurgitation at least twice a week.
RESULTS: After professional translation, the Italian RDQ was judged to retain fully the meaning of the original RDQ. Internal consistency, as judged by the (Cronbach's alpha) was satisfactory, with an overall RDQ scale alpha=0.86 (minimum acceptable value=0.70). Test--retest reliability (Spearman coefficient) was again found to be optimal, with individual item values ranging between 0.74 (for 'pain in the upper stomach: frequency') and 0.90 (for 'burning feeling behind breastbone: severity'). Finally, the correlation coefficient was 0.96 for the total scale and a range of 0.85-0.98 for individual items, indicating extremely satisfactory concordance.
CONCLUSIONS: The Italian RDQ appears to be a simple, reproducible, and reliable tool for the diagnosis of GERD. We believe that this questionnaire is well suited for use, both in primary care settings and in epidemiological studies, in particular for the assessment of so-called typical symptoms.

Entities:  

Mesh:

Year:  2008        PMID: 18301298     DOI: 10.1097/MEG.0b013e3282f246b2

Source DB:  PubMed          Journal:  Eur J Gastroenterol Hepatol        ISSN: 0954-691X            Impact factor:   2.566


  3 in total

1.  [Modern diagnostic tools for esophageal pathologies].

Authors:  A Kandulski; P Malfertheiner; J Weigt
Journal:  Internist (Berl)       Date:  2013-03       Impact factor: 0.743

2.  Dexlansoprazole for Heartburn Relief in Adolescents with Symptomatic, Nonerosive Gastro-esophageal Reflux Disease.

Authors:  Benjamin D Gold; Betsy Pilmer; Jaroslaw Kierkuś; Barbara Hunt; Maria Claudia Perez; David Gremse
Journal:  Dig Dis Sci       Date:  2017-09-15       Impact factor: 3.199

3.  Randomised clinical trial: mucosal protection combined with acid suppression in the treatment of non-erosive reflux disease - efficacy of Esoxx, a hyaluronic acid-chondroitin sulphate based bioadhesive formulation.

Authors:  V Savarino; F Pace; C Scarpignato
Journal:  Aliment Pharmacol Ther       Date:  2017-01-24       Impact factor: 8.171

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.