Literature DB >> 18301280

Optic disc hemorrhages in glaucoma and ocular hypertension: implications and recommendations.

Tara A Uhler1, Jody Piltz-Seymour.   

Abstract

PURPOSE OF REVIEW: To describe the epidemiology of disc hemorrhages and underscore the importance of detecting these markers of potential glaucomatous damage and progression. RECENT
FINDINGS: The Ocular Hypertension Treatment Study has confirmed that disc hemorrhages are an independent risk factor in the development of glaucoma. The risk of developing glaucoma was six times more likely in ocular hypertensive patients with disc hemorrhages compared with ocular hypertensive patients without disc hemorrhages. This study also highlighted the difficulty in detecting disc hemorrhages on clinical examination, noting that only 16% of disc hemorrhages detected on stereophotographs were identified on funduscopic examination. One study has demonstrated that surgical lowering of intraocular pressure decreased the occurrence of disc hemorrhages.
SUMMARY: Although the mechanism for the development of disc hemorrhages remains vague, the recent literature describes the difficulty in detecting disc hemorrhages, the importance of identifying this negative prognostic indicator and the effectiveness of intraocular pressure lowering with trabeculectomy in decreasing the risk of future disc hemorrhages.

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Year:  2008        PMID: 18301280     DOI: 10.1097/ICU.0b013e3282f3e6bc

Source DB:  PubMed          Journal:  Curr Opin Ophthalmol        ISSN: 1040-8738            Impact factor:   3.761


  16 in total

Review 1.  Neuroinflammation in glaucoma: A new opportunity.

Authors:  Pete A Williams; Nick Marsh-Armstrong; Gareth R Howell
Journal:  Exp Eye Res       Date:  2017-02-24       Impact factor: 3.467

2.  Thirteen-Year Follow-up of Optic Disc Hemorrhages in the Ocular Hypertension Treatment Study.

Authors:  Donald L Budenz; Julia Beiser Huecker; Steven J Gedde; Mae Gordon; Michael Kass
Journal:  Am J Ophthalmol       Date:  2016-11-07       Impact factor: 5.258

3.  The impact of disc hemorrhage studies on our understanding of glaucoma: a systematic review 50 years after the rediscovery of disc hemorrhage.

Authors:  Tetsuya Yamamoto
Journal:  Jpn J Ophthalmol       Date:  2018-11-21       Impact factor: 2.447

4.  Disc Hemorrhages Are Associated With the Presence and Progression of Glaucomatous Central Visual Field Defects.

Authors:  Aakriti G Shukla; Portia E Sirinek; C Gustavo De Moraes; Dana M Blumberg; George A Cioffi; Alon Skaat; Christopher A Girkin; Robert N Weinreb; Linda M Zangwill; Donald C Hood; Jeffrey M Liebmann
Journal:  J Glaucoma       Date:  2020-06       Impact factor: 2.503

Review 5.  An examination of the hypothesis that intraocular pressure elevation episodes can have prognostic significance in glaucoma suspects.

Authors:  Charles McMonnies
Journal:  J Optom       Date:  2014-09-04

6.  Prevalence of optic disc haemorrhages in an elderly UK Caucasian population and possible association with reticular pseudodrusen-the Bridlington Eye Assessment Project (BEAP): a cross-sectional study (2002-2006).

Authors:  Craig Wilde; Ali Poostchi; Rajesh Narendran; Hamish K MacNab; Jonathan G Hillman; Phillip Alexander; Winfried M Amoaku; Stephen A Vernon
Journal:  Eye (Lond)       Date:  2018-11-01       Impact factor: 3.775

7.  Comparison of myopic and nonmyopic disc hemorrhage in primary open-angle glaucoma.

Authors:  Ho Soong Kim; Ki Ho Park; Jin Wook Jeoung; Joohyun Park
Journal:  Jpn J Ophthalmol       Date:  2012-11-27       Impact factor: 2.447

8.  Immunomodulation as a Neuroprotective Strategy for Glaucoma Treatment.

Authors:  Mine Bariş; Gülgün Tezel
Journal:  Curr Ophthalmol Rep       Date:  2019-04-23

Review 9.  Ginkgo biloba: an adjuvant therapy for progressive normal and high tension glaucoma.

Authors:  A K Cybulska-Heinrich; M Mozaffarieh; J Flammer
Journal:  Mol Vis       Date:  2012-02-09       Impact factor: 2.367

Review 10.  Molecular regulation of neuroinflammation in glaucoma: Current knowledge and the ongoing search for new treatment targets.

Authors:  Gülgün Tezel
Journal:  Prog Retin Eye Res       Date:  2021-08-01       Impact factor: 21.198

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