| Literature DB >> 18300015 |
Alonso Martínez-Canabal1, Mariana Angoa-Pérez, Concepción Rugerio-Vargas, Gabino Borgonio-Perez, Selva Rivas-Arancibia.
Abstract
The aim of this study was to determine GH-effects on Cyclooxygenase-2 (COX-2) expression on hippocampus alterations caused by ozone exposure. Seventy male rats were divided into: (1) control; (2) exposed to ozone for 7, 15, and 30 days; (3) exposed to ozone and treated with GH, for 7, 15, and 30 days. Results showed that lipoperoxidation levels and number of COX-2-positive cells increased in all groups exposed to ozone compared to control. In the groups treated with GH, COX-2 immunoreactive cell number decreased with respect to the ozone group. Therefore, GH could provide protection against damage induced by oxidative stress.Entities:
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Year: 2008 PMID： 18300015 DOI： 10.1080/00207450701593160
Source DB: PubMed Journal: Int J Neurosci ISSN： 0020-7454 Impact factor: 2.292