Literature DB >> 18299876

An epidemic of sticky silicone oil at the Rotterdam Eye Hospital. Patient review and chemical analyses.

Marc A Veckeneer1, Simone de Voogd, Eric W Lindstedt, Dirk-Henning Menz, Jan C van Meurs.   

Abstract

PURPOSE: To report and study the phenomenon of abnormal silicone oil adherent to the retina at the time of removal in a number of patients.
MATERIALS AND METHODS: Chart review was performed to identify possible patient or procedural factors that could predispose to sticky silicone oil formation. Gas chromatography-mass spectroscopy and nuclear magnetic resonance spectroscopy analyses were performed on sticky silicone oil samples, on perfluorocarbon liquid and on silicone oil samples straight from the vial.
RESULTS: Sticky silicone oil remnants were seen on the retina in 28 out of 234 silicone oil removal procedures between January 2001 and November 2002. Forceful removal was complicated in two patients by a choroidal hemorrhage and in one patient by a retinal tear. The use of perfluoro-octane (PFO; C(8)F(18)) rather than perfluorodecalin (C(10)F(18)) was related to the phenomenon (P < 0.001). Gas chromatography-mass spectroscopy analysis revealed a significant presence of PFO in samples of sticky silicone oil, and traces of partially fluorinated carbon liquid were found in the sticky oil as well as in the PFO samples.
CONCLUSIONS: The use of PFO may have been a predisposing factor for the occurrence of sticky silicone oil. While the presence of silicone oil remnants on the retina did not cause lasting side effect, forceful attempts at removal can lead to complications.

Entities:  

Mesh:

Substances:

Year:  2008        PMID: 18299876     DOI: 10.1007/s00417-008-0768-9

Source DB:  PubMed          Journal:  Graefes Arch Clin Exp Ophthalmol        ISSN: 0721-832X            Impact factor:   3.117


  10 in total

1.  In vivo formation of heavy oil.

Authors:  T J Sleep; A J Luff
Journal:  Retina       Date:  1999       Impact factor: 4.256

2.  Interaction of different ocular endotamponades as a risk factor for silicone oil emulsification.

Authors:  Joachim H Dresp; Dirk-Henning Menz
Journal:  Retina       Date:  2005 Oct-Nov       Impact factor: 4.256

3.  An agglutination assay using emulsified oils.

Authors:  T L Prather; J Grande; C R Keese; I Giaever
Journal:  J Immunol Methods       Date:  1986-03-13       Impact factor: 2.303

4.  Combined use of partially fluorinated alkanes, perfluorocarbon liquids and silicone oil: an experimental study.

Authors:  H Hoerauf; K Kobuch; J Dresp; D H Menz
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2001-06       Impact factor: 3.117

5.  Determination of the solubility of perfluorocarbon liquids in silicone oil in vitro and in vivo.

Authors:  Hans Hoerauf; Frank Faude; Dirk-Henning Menz; Joachim Dresp; Peter Wiedemann; Horst Laqua
Journal:  Retina       Date:  2002-04       Impact factor: 4.256

6.  Quantification of intraocular retained perfluorodecalin after macroscopic complete removal.

Authors:  M Winter; C Winter; B Wiechens
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1999-02       Impact factor: 3.117

7.  Fibroblast behavior at aqueous interfaces with perfluorocarbon, silicone, and fluorosilicone liquids.

Authors:  J R Sparrow; R Ortiz; P R MacLeish; S Chang
Journal:  Invest Ophthalmol Vis Sci       Date:  1990-04       Impact factor: 4.799

8.  Intraocular dispersion of perfluorocarbon liquids in silicone oil.

Authors:  Antonio P Ciardella; Kevin Langton; Stanley Chang
Journal:  Am J Ophthalmol       Date:  2003-08       Impact factor: 5.258

9.  Experimental studies of tolerance to intravitreal perfluoro-n-octane liquid.

Authors:  S Chang; J R Sparrow; T Iwamoto; A Gershbein; R Ross; R Ortiz
Journal:  Retina       Date:  1991       Impact factor: 4.256

10.  Experimental intraocular tolerance to liquid perfluorooctane and perfluoropolyether.

Authors:  C Eckardt; U Nicolai; M Winter; E Knop
Journal:  Retina       Date:  1991       Impact factor: 4.256

  10 in total
  12 in total

1.  [Advantages and disadvantages of heavy silicone oil].

Authors:  B Kirchhof
Journal:  Ophthalmologe       Date:  2010-06       Impact factor: 1.059

Review 2.  [Toxicity of heavy liquids].

Authors:  Kai Januschowski; Peter Szurman; Koen Willekens; Michael J Bojdys; Karl Boden
Journal:  Ophthalmologe       Date:  2019-10       Impact factor: 1.059

3.  Colored perfluorocarbon liquids as novel intraoperative tools.

Authors:  Stanislao Rizzo; Claudia Belting; Federica Genovesi-Ebert; Nadine Hagedorn
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2011-12-02       Impact factor: 3.117

4.  New technique for removal of perfluorocarbon liquid related sticky silicone oil and literature review.

Authors:  Hai-Shuang Lin; Yong-Ping Tang; Lu Zhang; En-Ze Liu; Ling-Ying Ye; Ming-Na Xu; Rong-Han Wu; Zhi-Xiang Hu
Journal:  Int J Ophthalmol       Date:  2021-12-18       Impact factor: 1.779

Review 5.  [Heavy liquids as intraoperative instrument in retinal surgery].

Authors:  Karl Boden; K Januschowski; P Szurman
Journal:  Ophthalmologe       Date:  2019-10       Impact factor: 1.059

Review 6.  Biocompatibility of intraocular liquid tamponade agents: an update.

Authors:  Mario R Romano; Mariantonia Ferrara; Irene Nepita; Jana D'Amato Tothova; Alberto Giacometti Schieroni; Daniela Reami; Raniero Mendichi; Libero Liggieri; Rodolfo Repetto
Journal:  Eye (Lond)       Date:  2021-05-25       Impact factor: 4.456

Review 7.  Inflammation induced by perfluorocarbon liquid: intra- and postoperative use.

Authors:  Marta S Figueroa; Diego Ruiz Casas
Journal:  Biomed Res Int       Date:  2014-03-24       Impact factor: 3.411

Review 8.  Vitreous tamponades in highly myopic eyes.

Authors:  X Valldeperas; J Lorenzo-Carrero
Journal:  Biomed Res Int       Date:  2014-06-02       Impact factor: 3.411

9.  The Effect of Temperature Changes in Vitreoretinal Surgery.

Authors:  Mario R Romano; Vito Romano; Alessandro Mauro; Martina Angi; Ciro Costagliola; Luigi Ambrosone
Journal:  Transl Vis Sci Technol       Date:  2016-02-09       Impact factor: 3.283

Review 10.  Perfluorocarbon liquid: its application in vitreoretinal surgery and related ocular inflammation.

Authors:  Qi Yu; Kun Liu; Li Su; Xin Xia; Xun Xu
Journal:  Biomed Res Int       Date:  2014-03-30       Impact factor: 3.411

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.