Literature DB >> 18298779

Outcome of hospital deliveries of women living at high altitude: a study from Lhasa in Tibet.

Yeshe Yangzom1, Liling Qian, Mina Shan, Ya La, Deji Meiduo, Xiaoying Hu, Qiong Da, Bo Sun, Rolf Zetterström.   

Abstract

AIM: To describe rates of neonatal mortality, low birthweight (LBW), preterm birth and small for gestational age (SGA), and relate outcome to ethnicity and perinatal risk factors of liveborn infants of hospital deliveries in Lhasa. The differences in these variables between ethnic Tibetans and non-Tibetans were also studied.
METHODS: Data were prospectively collected on the outcome of all liveborn infants born in four hospitals in the urban area of Lhasa, Tibet, in 2005. RESULT: A total of 2540 liveborn infants were recorded. The rates of LBW, preterm birth and SGA were 13.6%, 5.7% and 22.2%, respectively. Neonatal mortality rate was 42/1000 for the infants born alive in the hospitals. Lower GA, vaginal delivery, foetal distress and lack of prenatal care, but not ethnicity, were associated with increased risk of death in multivariate logistic regression. Tibetans had higher BW and lower rates of LBW, SGA, need of oxygen supplementation and maternal hypertension, but higher rates of foetal distress, caesarean section, multiple births and low Apgar scores.
CONCLUSION: This study provided a profile of perinatal-neonatal care of hospital newborn infants in Lhasa, Tibet. The rates of neonatal mortality, LBW and SGA were high. The findings suggest ethnic differences in perinatal-neonatal adaptation to high altitude.

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Year:  2008        PMID: 18298779     DOI: 10.1111/j.1651-2227.2008.00628.x

Source DB:  PubMed          Journal:  Acta Paediatr        ISSN: 0803-5253            Impact factor:   2.299


  9 in total

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Review 4.  Measuring high-altitude adaptation.

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Journal:  J Appl Physiol (1985)       Date:  2017-08-31

Review 5.  Evolutionary adaptation to high altitude: a view from in utero.

Authors:  Colleen Glyde Julian; Megan J Wilson; Lorna G Moore
Journal:  Am J Hum Biol       Date:  2009 Sep-Oct       Impact factor: 1.937

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7.  Surfactant Therapy for Respiratory Distress Syndrome in High- and Ultra-High-Altitude Settings.

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Journal:  Front Pediatr       Date:  2022-03-04       Impact factor: 3.418

8.  How Placenta Promotes the Successful Reproduction in High-Altitude Populations: A Transcriptome Comparison between Adaptation and Acclimatization.

Authors:  Deng Wu; Yunao Liu; Wei Chen; Jianming Shao; Pubu Zhuoma; Dexiong Zhao; Yang Yu; Tianzi Liu; Ruoxuan Yu; Yongna Gan; Baima Yuzheng; Yongshu Huang; Haikun Zhang; Xiaoman Bi; Chengcheng Tao; Shujuan Lai; Qiaoxia Luo; Dake Zhang; Hongmei Wang; Pingcuo Zhaxi; Jianqing Zhang; Jie Qiao; Changqing Zeng
Journal:  Mol Biol Evol       Date:  2022-06-02       Impact factor: 8.800

Review 9.  Hypoxia at the heart of sudden infant death syndrome?

Authors:  Marianne T Neary; Ross A Breckenridge
Journal:  Pediatr Res       Date:  2013-07-17       Impact factor: 3.756

  9 in total

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