Literature DB >> 18298051

Neisseria meningitidis strains from patients with invasive meningococcal disease differ in stimulation of cytokine production.

M Holub1, M Scheinostová, O Dzupová, A Fiserová, O Beran, J Kalmusová, M Musilek, P Krízová.   

Abstract

Cytokine production was determined in vitro after stimulation with three different Neisseria meningitidis (NM) strains. Virulent NM B strain isolated from a patient with mild course of invasive meningococcal disease (IMD) elicited higher cytokine production than NM B and NM C hypervirulent strains isolated from patients with moderate and fatal course of IMD, respectively. Endotoxin concentration after in vitro stimulation correlated with cytokine production: the highest endotoxin levels were observed with virulent NM B strain. Serum cytokines and endotoxin levels showed an opposite trend. These results suggest that inflammatory response during IMD is predominantly influenced by host factors.

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Year:  2007        PMID: 18298051     DOI: 10.1007/BF02932114

Source DB:  PubMed          Journal:  Folia Microbiol (Praha)        ISSN: 0015-5632            Impact factor:   2.629


  11 in total

Review 1.  The immunopathogenesis of meningococcal disease.

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Review 2.  Update on meningococcal disease with emphasis on pathogenesis and clinical management.

Authors:  M van Deuren; P Brandtzaeg; J W van der Meer
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3.  Tumour necrosis factor alpha antibody protects against lethal meningococcaemia.

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Review 8.  Genetic basis for biosynthesis, structure, and function of meningococcal lipooligosaccharide (endotoxin).

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4.  Sequential analysis of biomarkers in cerebrospinal fluid and serum during invasive meningococcal disease.

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