Literature DB >> 18296454

Bicuspid aortic valve: a literature review and its impact on sport activity.

Paola De Mozzi1, Umile Giuseppe Longo, Giorgio Galanti, Nicola Maffulli.   

Abstract

The bicuspid aortic valve (BAV) is the most common congenital cardiac malformation. A literature search was performed using the key words 'bicuspid aortic valve', 'pathophysiology', 'exercise' and 'training'. BAV is the result of a complex developmental process where several genes seem to lead to abnormal valvulogenesis. Complications associated with BAV include aortic stenosis (AS) and regurgitation, infective endocarditis and aortic dilation and dissection. Moreover, BAV may be associated with other cardiovascular anomalies, mainly aortic coarctation. There is greater awareness of BAV in the young population who practice sport, with an increasing interest on the impact of regular and competitive exercise on athletes with BAV. The early identification of BAV through pre-participation screening is of paramount importance, and the justification of the more appropriate diagnostic methods is still an area of debate. A normally functioning BAV usually does not represent a limit for practising sport. The stress of regular and intense exercise on an abnormal aortic valve may favour its early deterioration and accelerate the development of complications. Therefore, athletes with BAV warrant regular follow-up, which should include echocardiographic assessment at least every year. The eligibility for participation and ability to continue to practise competitive sports in athletes with BAV cannot be generalized, but needs to be individualized depending on age, severity of lesions and type of sport. Further studies are required to elucidate the impact of physical training and competitive sports on the natural course of the BAV.

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Year:  2008        PMID: 18296454     DOI: 10.1093/bmb/ldn002

Source DB:  PubMed          Journal:  Br Med Bull        ISSN: 0007-1420            Impact factor:   4.291


  18 in total

1.  Loss of Gata5 in mice leads to bicuspid aortic valve.

Authors:  Brigitte Laforest; Gregor Andelfinger; Mona Nemer
Journal:  J Clin Invest       Date:  2011-07       Impact factor: 14.808

2.  Bicuspid aortic valve hemodynamics does not promote remodeling in porcine aortic wall concavity.

Authors:  Samantha K Atkins; Alison N Moore; Philippe Sucosky
Journal:  World J Cardiol       Date:  2016-01-26

3.  Etiology of bicuspid aortic valve disease: Focus on hemodynamics.

Authors:  Samantha K Atkins; Philippe Sucosky
Journal:  World J Cardiol       Date:  2014-12-26

4.  Genetically alike Syrian hamsters display both bifoliate and trifoliate aortic valves.

Authors:  Valentín Sans-Coma; M Carmen Fernández; Borja Fernández; Ana C Durán; Robert H Anderson; Josep M Arqué
Journal:  J Anat       Date:  2011-10-30       Impact factor: 2.610

5.  The bicuspid aortic valve and its relation to aortic dilation.

Authors:  Shi-Min Yuan; Hua Jing; Jacob Lavee
Journal:  Clinics (Sao Paulo)       Date:  2010-05       Impact factor: 2.365

6.  Clinical outcome, valve dysfunction, and progressive aortic dilation in a pediatric population with isolated bicuspid aortic valve.

Authors:  Gaia Spaziani; Piercarlo Ballo; Silvia Favilli; Veronica Fibbi; Lorenzo Buonincontri; Iva Pollini; Alfredo Zuppiroli; Enrico Chiappa
Journal:  Pediatr Cardiol       Date:  2013-12-21       Impact factor: 1.655

7.  Musculoskeletal problems in soccer players: current concepts.

Authors:  Umile Giuseppe Longo; Mattia Loppini; Roberta Cavagnino; Nicola Maffulli; Vincenzo Denaro
Journal:  Clin Cases Miner Bone Metab       Date:  2012-09-30

8.  Bicuspid aortic valve with critical coarctation of the aorta: single- or two-stage operation?

Authors:  Hongqiang Zhang; Kai Zhu; Shouguo Yang; Junyu Zhai; Tianyu Zhou; Xiaoning Sun; Chunsheng Wang
Journal:  J Thorac Dis       Date:  2018-07       Impact factor: 2.895

9.  Genetic insights into bicuspid aortic valve formation.

Authors:  Brigitte Laforest; Mona Nemer
Journal:  Cardiol Res Pract       Date:  2012-06-04       Impact factor: 1.866

10.  Tissue engineered strategies for pseudoarthrosis.

Authors:  Umile Giuseppe Longo; Ugo Trovato; Mattia Loppini; Giacomo Rizzello; Wasim Sardar Khan; Nicola Maffulli; Vincenzo Denaro
Journal:  Open Orthop J       Date:  2012-11-30
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