Literature DB >> 18296075

Understanding the pain experience in hip and knee osteoarthritis--an OARSI/OMERACT initiative.

G A Hawker1, L Stewart, M R French, J Cibere, J M Jordan, L March, M Suarez-Almazor, R Gooberman-Hill.   

Abstract

OBJECTIVE: To examine the pain experience of people with hip or knee osteoarthritis (OA), particularly changes over time and most distressing features.
METHOD: Focus groups in individuals aged 40+ years with painful hip or knee OA obtained detailed descriptions of OA pain from early to late disease. A modified Patient Generated Index (PGI) was used to assess the features of OA pain that participants found most distressing. Content analysis was performed to examine response patterns; descriptive statistics were used to summarize PGI responses.
RESULTS: Mean age of the 143 participants (52 hip OA; 91 knee OA) was 69.5 years (47-92 years); 60.8% were female and 93.7% Caucasian. Participants described two distinct types of pain - a dull, aching pain, which became more constant over time, punctuated increasingly with short episodes of a more intense, often unpredictable, emotionally draining pain. The latter, but not the former, resulted in significant avoidance of social and recreational activities. From PGI responses, distressing pain features were: the pain itself (particularly intense and unpredictable pain) and the pain's impact on mobility, mood and sleep.
CONCLUSIONS: Two distinct pain types were identified. Intermittent intense pain, particularly when unpredictable, had the greatest impact on quality of life.

Entities:  

Mesh:

Year:  2008        PMID: 18296075     DOI: 10.1016/j.joca.2007.12.017

Source DB:  PubMed          Journal:  Osteoarthritis Cartilage        ISSN: 1063-4584            Impact factor:   6.576


  137 in total

1.  Prospective change in daily walking over 2 years in older adults with or at risk of knee osteoarthritis: the MOST study.

Authors:  D K White; C Tudor-Locke; Y Zhang; J Niu; D T Felson; K D Gross; M C Nevitt; C E Lewis; J Torner; T Neogi
Journal:  Osteoarthritis Cartilage       Date:  2015-08-28       Impact factor: 6.576

Review 2.  Osteoarthritis pain: What are we learning from animal models?

Authors:  Rachel E Miller; Anne-Marie Malfait
Journal:  Best Pract Res Clin Rheumatol       Date:  2018-04-26       Impact factor: 4.098

3.  Development and preliminary psychometric testing of a new OA pain measure--an OARSI/OMERACT initiative.

Authors:  G A Hawker; A M Davis; M R French; J Cibere; J M Jordan; L March; M Suarez-Almazor; J N Katz; P Dieppe
Journal:  Osteoarthritis Cartilage       Date:  2008-04       Impact factor: 6.576

4.  Dynamic weight-bearing assessment of pain in knee osteoarthritis: a reliability and agreement study.

Authors:  Louise Klokker; Robin Christensen; Richard Osborne; Elisabeth Ginnerup; Eva E Waehrens; Henning Bliddal; Marius Henriksen
Journal:  Qual Life Res       Date:  2015-06-06       Impact factor: 4.147

5.  The synovial fluid adiponectin-leptin ratio predicts pain with knee osteoarthritis.

Authors:  Rajiv Gandhi; Mark Takahashi; Holly Smith; Randy Rizek; Nizar N Mahomed
Journal:  Clin Rheumatol       Date:  2010-03-28       Impact factor: 2.980

6.  Peripheral and Central Sensitization of Pain in Individuals With Hand Osteoarthritis and Associations With Self-Reported Pain Severity.

Authors:  Pernille Steen Pettersen; Tuhina Neogi; Karin Magnusson; Hilde Berner Hammer; Till Uhlig; Tore K Kvien; Ida K Haugen
Journal:  Arthritis Rheumatol       Date:  2019-05-14       Impact factor: 10.995

Review 7.  Towards a mechanism-based approach to pain management in osteoarthritis.

Authors:  Anne-Marie Malfait; Thomas J Schnitzer
Journal:  Nat Rev Rheumatol       Date:  2013-09-17       Impact factor: 20.543

8.  Changes in Abeta non-nociceptive primary sensory neurons in a rat model of osteoarthritis pain.

Authors:  Qi Wu; James L Henry
Journal:  Mol Pain       Date:  2010-07-01       Impact factor: 3.395

9.  Delayed onset of changes in soma action potential genesis in nociceptive A-beta DRG neurons in vivo in a rat model of osteoarthritis.

Authors:  Qi Wu; James L Henry
Journal:  Mol Pain       Date:  2009-09-28       Impact factor: 3.395

10.  Association between radiographic features of knee osteoarthritis and pain: results from two cohort studies.

Authors:  Tuhina Neogi; David Felson; Jingbo Niu; Michael Nevitt; Cora E Lewis; Piran Aliabadi; Burt Sack; James Torner; Lawrence Bradley; Yuqing Zhang
Journal:  BMJ       Date:  2009-08-21
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