Studies of cardiovascular and arterial blood gas changes during carbon dioxide pneumoperitoneum for laparoscopic sterilization under general anaesthesia versus local anaesthesia.

This study was conducted to evaluate the different change in arterial blood gases and cardiovascular system in 50 healthy females during laparoscopic sterilization procedure performed under general or local anaesthesia. Women who had laparoscopic sterilization under local anaesthesia, showed an increase in respiratory rate by 17% in response to hypercarbia produced by carbon dioxide insufflation. Subjects undergoing laparoscopic sterilization under general anaesthesia showed significant rise in pulse rate by 6% and systolic and diastolic blood pressure by 8% and 14%, respectively. Also arterial blood gas analysis showed increase in PaO2 by 22.7% which was highly significant. However, PaCO2, pH and base were maintained within normal limits as compared to the other group done under local anaesthesia, where no changes were observed.