Literature DB >> 18296005

Electrocardiographic findings of acute organophosphate poisoning.

Yusuf Yurumez1, Yucel Yavuz, Hayrettin Saglam, Polat Durukan, Seda Ozkan, Okhan Akdur, Murat Yucel.   

Abstract

In this study, we evaluated 85 patients who presented to our Emergency Department with organophosphate (OP) poisoning and discuss their associated electrocardiographic (ECG) abnormalities. Over a period of 3 years, 85 patients with OP poisoning were included in this retrospective study. ECG analysis included the rate, rhythm, ST-T abnormalities, conduction defects, and measurement of PR and QT intervals. The mean age was 32.2 +/- 14.9 years. Sixty percent of the patients were female. The mean corrected QT interval (QTc interval) was 0.435 +/- 0.052 s. Prolongation of the QTc interval (55.5%) was the most common ECG abnormality, followed by sinus tachycardia (31.8%). Elevation of the ST segment and low amplitude T waves were seen in 15 cases (17.6%). Patients with OP poisoning might reveal ECG abnormalities such as QTc interval prolongation or non-specific ST-T changes. QTc interval prolongation cannot be used as a unique predictive factor in determining short-term prognosis in OP poisoning. We found no clear relation between OP poisoning-related malignant ventricular dysrhythmia and QTc interval.

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Year:  2008        PMID: 18296005     DOI: 10.1016/j.jemermed.2007.08.063

Source DB:  PubMed          Journal:  J Emerg Med        ISSN: 0736-4679            Impact factor:   1.484


  6 in total

1.  Intramuscular atenolol and levetiracetam reduce mortality in a rat model of paraoxon-induced status epilepticus.

Authors:  Laxmikant S Deshpande; Robert E Blair; Matthew Halquist; Leon Kosmider; Robert J DeLorenzo
Journal:  Ann N Y Acad Sci       Date:  2020-09-22       Impact factor: 5.691

Review 2.  Clinical features of organophosphate poisoning: A review of different classification systems and approaches.

Authors:  John Victor Peter; Thomas Isiah Sudarsan; John L Moran
Journal:  Indian J Crit Care Med       Date:  2014-11

3.  Acute Atrial Fibrillation Complicating Organophosphorus Poisoning.

Authors:  Monika Maheshwari; Shreekant Chaudhary
Journal:  Heart Views       Date:  2017 Jul-Sep

4.  Cardiac injury in organophosphate poisoning after acute ingestion.

Authors:  Ashok Kumar Pannu; Ashish Bhalla; R I Vishnu; Sahil Garg; Deba Prasad Dhibar; Navneet Sharma; Rajesh Vijayvergiya
Journal:  Toxicol Res (Camb)       Date:  2021-04-26       Impact factor: 3.524

5.  Recent advances in the treatment of organophosphorous poisonings.

Authors:  Mahdi Balali-Mood; Hamidreza Saber
Journal:  Iran J Med Sci       Date:  2012-06

6.  Heart rate-corrected QT interval helps predict mortality after intentional organophosphate poisoning.

Authors:  Shou-Hsuan Liu; Ja-Liang Lin; Cheng-Hao Weng; Huang-Yu Yang; Ching-Wei Hsu; Kuan-Hsing Chen; Wen-Hung Huang; Tzung-Hai Yen
Journal:  PLoS One       Date:  2012-05-04       Impact factor: 3.240

  6 in total

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