Literature DB >> 18295599

Identification of boronic acids as antagonists of bacterial quorum sensing in Vibrio harveyi.

Nanting Ni1, Han-Ting Chou, Junfeng Wang, Minyong Li, Chung-Dar Lu, Phang C Tai, Binghe Wang.   

Abstract

Bacterial quorum sensing plays a very important role in the regulation of biofilm formation, virulence, conjugation, sporulation, and swarming mobility. Inhibitors of bacterial quorum sensing are important research tools and potential therapeutic agents. In this paper, we describe for the first time the discovery of several boronic acids as single digit micromolar inhibitors of bacterial quorum sensing in Vibrio harveyi.

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Year:  2008        PMID: 18295599     DOI: 10.1016/j.bbrc.2008.02.061

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  7 in total

Review 1.  Exploiting quorum sensing to confuse bacterial pathogens.

Authors:  Breah LaSarre; Michael J Federle
Journal:  Microbiol Mol Biol Rev       Date:  2013-03       Impact factor: 11.056

2.  Medicinal chemistry as a conduit for the modulation of quorum sensing.

Authors:  Colin A Lowery; Nicholas T Salzameda; Daisuke Sawada; Gunnar F Kaufmann; Kim D Janda
Journal:  J Med Chem       Date:  2010-11-11       Impact factor: 7.446

3.  Click with a boronic acid handle: a neighboring group-assisted click reaction that allows ready secondary functionalization.

Authors:  Alexander B Draganov; Ke Wang; Jalisa Holmes; Krishna Damera; Danzhu Wang; Chaofeng Dai; Binghe Wang
Journal:  Chem Commun (Camb)       Date:  2015-10-21       Impact factor: 6.222

4.  Small molecule inhibitors of AI-2 signaling in bacteria: state-of-the-art and future perspectives for anti-quorum sensing agents.

Authors:  Min Guo; Sonja Gamby; Yue Zheng; Herman O Sintim
Journal:  Int J Mol Sci       Date:  2013-08-29       Impact factor: 5.923

Review 5.  Combining Biofilm-Controlling Compounds and Antibiotics as a Promising New Way to Control Biofilm Infections.

Authors:  Andréia Bergamo Estrela; Wolf-Rainer Abraham
Journal:  Pharmaceuticals (Basel)       Date:  2010-05-11

6.  In situ targeted MRI detection of Helicobacter pylori with stable magnetic graphitic nanocapsules.

Authors:  Yunjie Li; Xiaoxiao Hu; Ding Ding; Yuxiu Zou; Yiting Xu; Xuewei Wang; Yin Zhang; Long Chen; Zhuo Chen; Weihong Tan
Journal:  Nat Commun       Date:  2017-06-15       Impact factor: 14.919

7.  High-Throughput Virtual Screening for a New Class of Antagonist Targeting LasR of Pseudomonas aeruginosa.

Authors:  Aishwarya Vetrivel; Santhi Natchimuthu; Vidyalakshmi Subramanian; Rajeswari Murugesan
Journal:  ACS Omega       Date:  2021-07-08
  7 in total

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