PURPOSE: To evaluate the levels of serum alpha 1-antitrypsin in patients with pseudoexfoliation syndrome (PEX) and healthy control subjects without PEX. MATERIAL AND METHODS: Forty-four patient with PEX and 40 healthy control subjects (84 subjects total) were enrolled into the study. Serum ATT levels were measured using nephelometry. RESULTS: The mean serum AAT concentration in PEX group was significantly higher than in the controls (p=0.0001). CONCLUSION: Serum AAT levels were found to be increased in patients with PEX. Increased serum AAT levels in PEX may explain the role of inflammation in this group of patients.
PURPOSE: To evaluate the levels of serum alpha 1-antitrypsin in patients with pseudoexfoliation syndrome (PEX) and healthy control subjects without PEX. MATERIAL AND METHODS: Forty-four patient with PEX and 40 healthy control subjects (84 subjects total) were enrolled into the study. Serum ATT levels were measured using nephelometry. RESULTS: The mean serum AAT concentration in PEX group was significantly higher than in the controls (p=0.0001). CONCLUSION: Serum AAT levels were found to be increased in patients with PEX. Increased serum AAT levels in PEX may explain the role of inflammation in this group of patients.
Authors: Altaf A Kondkar; Taif A Azad; Faisal A Almobarak; Hatem Kalantan; Saleh A Al-Obeidan; Khaled K Abu-Amero Journal: Clin Ophthalmol Date: 2018-01-17