BACKGROUND/AIMS: Bile leakage after partial liver resection still is a common complication and is associated with substantial morbidity and even mortality. METHODS: A total of 234 consecutive liver resections without biliary reconstruction, performed between January 1992 and December 2004, were analyzed for postoperative bile leakage. RESULTS: Postoperative bile leakage occurred in 6.8% of patients (16/234). In univariate analysis, male gender (p = 0.037), major liver resection (p = 0.004), right-sided hepatectomy (p = 0.005), prolonged operation time (p = 0.001), intraoperative blood loss >500 ml (p = 0.009), red cell transfusion (p = 0.02), tumor size (p = 0.026), duration of vascular occlusion (p = 0.03) and surgical irradicality (p = 0.001) were risk factors. No independent risk factors were associated with bile leakage after liver resection. Bile leakage originated from the resection plane in 10 patients (63%). Endoscopic biliary decompression was performed in 9 patients as initial treatment, and percutaneous drainage of the bile collection was used in 4 patients. Bile leakage resolved spontaneously in 3 patients. CONCLUSIONS: Bile leakage is a persisting complication and in this study occurred in 6.8% of patients after partial liver resection. Percutaneous drainage of bile collection with or without endoscopic biliary decompression are effective interventions in the management of most cases of bile leakage. Copyright (c) 2008 S. Karger AG, Basel.
BACKGROUND/AIMS: Bile leakage after partial liver resection still is a common complication and is associated with substantial morbidity and even mortality. METHODS: A total of 234 consecutive liver resections without biliary reconstruction, performed between January 1992 and December 2004, were analyzed for postoperative bile leakage. RESULTS: Postoperative bile leakage occurred in 6.8% of patients (16/234). In univariate analysis, male gender (p = 0.037), major liver resection (p = 0.004), right-sided hepatectomy (p = 0.005), prolonged operation time (p = 0.001), intraoperative blood loss >500 ml (p = 0.009), red cell transfusion (p = 0.02), tumor size (p = 0.026), duration of vascular occlusion (p = 0.03) and surgical irradicality (p = 0.001) were risk factors. No independent risk factors were associated with bile leakage after liver resection. Bile leakage originated from the resection plane in 10 patients (63%). Endoscopic biliary decompression was performed in 9 patients as initial treatment, and percutaneous drainage of the bile collection was used in 4 patients. Bile leakage resolved spontaneously in 3 patients. CONCLUSIONS: Bile leakage is a persisting complication and in this study occurred in 6.8% of patients after partial liver resection. Percutaneous drainage of bile collection with or without endoscopic biliary decompression are effective interventions in the management of most cases of bile leakage. Copyright (c) 2008 S. Karger AG, Basel.
Authors: Jan Bednarsch; Elisabeth Blüthner; Maciej Malinowski; Daniel Seehofer; Johann Pratschke; Martin Stockmann Journal: World J Surg Date: 2016-09 Impact factor: 3.352
Authors: Alison A Smith; Dominique J Monlezun; John Martinie; David Iannitti; Ioannis Konstantinidis; Michael Darden; Geoffrey Parker; Yuman Fong; Joseph F Buell Journal: World J Surg Date: 2020-05 Impact factor: 3.352