Unusual synthesis of carbohydrate sec-sec ether-linked pseudodisaccharides.

In this paper, we describe the synthesis of sec-sec ether-linked pseudodisaccharides by the coupling of various secondary carbohydrate alcohols with di-O-isopropylidene allose 3-O-triflate. Reactions proceeded with inversion of configuration to give the 3-substituted di-O-isopropylidene glucose derivatives. The crystal structure of a sec-sec ether-linked pseudodisaccharide is reported.