Literature DB >> 18290861

Impact of deprivation on cardiovascular risk factors in people with diabetes: an observational study.

S Wild1, F Macleod, J McKnight, G Watt, C Mackenzie, I Ford, A McConnachie, R S Lindsay.   

Abstract

AIM: To examine the influence of deprivation on prevalence of diabetes and of cardiovascular disease risk factors in people with diabetes.
METHODS: Cross-sectional study of 52 280 people in diabetes registers of Greater Glasgow and Lothian NHS Board areas linked to hospital admission data. Results Age- and sex-adjusted prevalence of diabetes increased from 2.3% in the least deprived quintile (Q1) to 3.3% in the most deprived quintile (Q5; P < 0.001), as did prevalence of vascular disease (Q1 20%, Q5 27%; P < 0.001). Prevalence of current smoking (Q1 13%, Q5 32%; P < 0.001), obesity (Q1 38%, Q5 51%; P < 0.001) and above-target glycated haemoglobin (HbA(1c); > or = 7.5%: Q1 46% vs. Q5 47%; P = 0.01) were higher in the most deprived quintile. In contrast, the proportion of people with above-target cholesterol were similar (proportion > or = 5.0 mmol/l: Q1 26%, Q5 24%; P = 0.07) and the proportion of people with above-target systolic blood pressure (SBP) was lower (SBP > or = 140 mmHg: Q1 44%, Q5 37%; P = 0.02) in the most deprived quintile. In people with diabetes and prevalent vascular disease, deprivation was associated with failure to reach cholesterol target [odds ratio cholesterol > or = 5.0 mmol/l: Q5 vs. Q1 1.23 (1.04-1.45) P = 0.013]. SBP and cholesterol were markedly lower compared with previous population surveys.
CONCLUSIONS: The burden of diabetes and vascular disease is greater in more deprived populations. Our data confirm a major advance in management of cholesterol and blood pressure management. Deprivation is still associated with failure to reach cholesterol targets in secondary prevention as well as higher prevalence of obesity and smoking.

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Year:  2008        PMID: 18290861     DOI: 10.1111/j.1464-5491.2008.02382.x

Source DB:  PubMed          Journal:  Diabet Med        ISSN: 0742-3071            Impact factor:   4.359


  15 in total

1.  The effect of deprivation and HbA1c on admission to hospital for diabetic ketoacidosis in type 1 diabetes.

Authors:  L Govan; E Maietti; B Torsney; O Wu; A Briggs; H M Colhoun; C M Fischbacher; G P Leese; J A McKnight; A D Morris; N Sattar; S H Wild; R S Lindsay
Journal:  Diabetologia       Date:  2012-06-26       Impact factor: 10.122

Review 2.  Cardiovascular risk.

Authors:  Rupert A Payne
Journal:  Br J Clin Pharmacol       Date:  2012-09       Impact factor: 4.335

3.  Area-based socioeconomic status, type 2 diabetes and cardiovascular mortality in Scotland.

Authors:  C A Jackson; N R V Jones; J J Walker; C M Fischbacher; H M Colhoun; G P Leese; R S Lindsay; J A McKnight; A D Morris; J R Petrie; N Sattar; S H Wild
Journal:  Diabetologia       Date:  2012-08-15       Impact factor: 10.122

4.  Effect of socioeconomic status on mortality among people with type 2 diabetes: a study from the Scottish Diabetes Research Network Epidemiology Group.

Authors:  Jeremy J Walker; Shona J Livingstone; Helen M Colhoun; Robert S Lindsay; John A McKnight; Andrew D Morris; John R Petrie; Sam Philip; Naveed Sattar; Sarah H Wild
Journal:  Diabetes Care       Date:  2011-03-18       Impact factor: 19.112

5.  Achieved levels of HbA1c and likelihood of hospital admission in people with type 1 diabetes in the Scottish population: a study from the Scottish Diabetes Research Network Epidemiology Group.

Authors:  Lindsay Govan; Olivia Wu; Andrew Briggs; Helen M Colhoun; Colin M Fischbacher; Graham P Leese; John A McKnight; Sam Philip; Naveed Sattar; Sarah H Wild; Robert S Lindsay
Journal:  Diabetes Care       Date:  2011-07-25       Impact factor: 19.112

6.  Socioeconomic position, type 2 diabetes and long-term risk of death.

Authors:  Else-Marie Dalsgaard; Mette V Skriver; Annelli Sandbaek; Mogens Vestergaard
Journal:  PLoS One       Date:  2015-05-05       Impact factor: 3.240

7.  Predicting risk of type 2 diabetes in England and Wales: prospective derivation and validation of QDScore.

Authors:  Julia Hippisley-Cox; Carol Coupland; John Robson; Aziz Sheikh; Peter Brindle
Journal:  BMJ       Date:  2009-03-17

8.  Area level deprivation is an independent determinant of prevalent type 2 diabetes and obesity at the national level in Germany. Results from the National Telephone Health Interview Surveys 'German Health Update' GEDA 2009 and 2010.

Authors:  Werner Maier; Christa Scheidt-Nave; Rolf Holle; Lars E Kroll; Thomas Lampert; Yong Du; Christin Heidemann; Andreas Mielck
Journal:  PLoS One       Date:  2014-02-27       Impact factor: 3.240

9.  Factors associated with statin treatment for the primary prevention of cardiovascular disease in people within 2 years following diagnosis of diabetes in Scotland, 2006-2008.

Authors:  N R V Jones; C M Fischbacher; B Guthrie; G Leese; R S Lindsay; J A McKnight; D Pearson; S Philip; N Sattar; S H Wild
Journal:  Diabet Med       Date:  2014-03-24       Impact factor: 4.359

10.  Trends in type 2 diabetes incidence and mortality in Scotland between 2004 and 2013.

Authors:  Stephanie H Read; Joannes J Kerssens; David A McAllister; Helen M Colhoun; Colin M Fischbacher; Robert S Lindsay; Rory J McCrimmon; John A McKnight; John R Petrie; Naveed Sattar; Sarah H Wild
Journal:  Diabetologia       Date:  2016-07-28       Impact factor: 10.122

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