Literature DB >> 18289111

Redox state of cytochrome c regulates cellular ROS and caspase cascade in permeablized cell model.

Min Li1, Ao-Jin Wang, Jian-Xing Xu.   

Abstract

In a permeablized cell system, oxidized cyt c is able to induce caspase cascade whereas reduced cyt c cannot. In in vitro experiments, oxidized cyt c can promote H(2)O(2) generation. It is suggested that the redox state of cyt c might regulate the initiation of apoptosis via regulation of cellular ROS level.

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Year:  2008        PMID： 18289111     DOI： 10.2174/092986608783489490

Source DB:  PubMed          Journal:  Protein Pept Lett        ISSN： 0929-8665            Impact factor:   1.890


  8 in total

1.  Putative mechanisms of antitumor activity of cyano-substituted heteroaryles in HeLa cells.

Authors:  Katja Ester; Fran Supek; Kristina Majsec; Marko Marjanović; David Lembo; Manuela Donalisio; Tomislav Šmuc; Ivana Jarak; Grace Karminski-Zamola; Marijeta Kralj
Journal:  Invest New Drugs       Date:  2010-11-03       Impact factor: 3.850

Review 2.  tRNA and cytochrome c in cell death and beyond.

Authors:  Yide Mei; Jeongsik Yong; Aaron Stonestrom; Xiaolu Yang
Journal:  Cell Cycle       Date:  2010-08-07       Impact factor: 4.534

3.  Mitochondrial Rac1 GTPase import and electron transfer from cytochrome c are required for pulmonary fibrosis.

Authors:  Heather L Osborn-Heaford; Alan J Ryan; Shubha Murthy; Ana-Monica Racila; Chao He; Jessica C Sieren; Douglas R Spitz; A Brent Carter
Journal:  J Biol Chem       Date:  2011-12-08       Impact factor: 5.157

Review 4.  The tangled circuitry of metabolism and apoptosis.

Authors:  Joshua L Andersen; Sally Kornbluth
Journal:  Mol Cell       Date:  2013-02-07       Impact factor: 17.970

5.  Dissociation of JNK Activation from Elevated Levels of Reactive Oxygen Species, Cytochrome c Release, and Cell Death in NGF-Deprived Sympathetic Neurons.

Authors:  Meagan J McManus; James L Franklin
Journal:  Mol Neurobiol       Date:  2016-12-12       Impact factor: 5.590

6.  Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c.

Authors:  Allyson E Vaughn; Mohanish Deshmukh
Journal:  Nat Cell Biol       Date:  2008-11-23       Impact factor: 28.824

7.  RNA interference-mediated FANCF silencing sensitizes OVCAR3 ovarian cancer cells to adriamycin through increased adriamycin-induced apoptosis dependent on JNK activation.

Authors:  Miao He; Hai-Gang Sun; Jun-Ying Hao; Yan-Lin Li; Jian-Kun Yu; Yuan-Yuan Yan; Lin Zhao; Na Li; Yan Wang; Xue-Feng Bai; Zhao-Jin Yu; Zhi-Hong Zheng; Xiao-Yi Mi; En-Hua Wang; Min-Jie Wei
Journal:  Oncol Rep       Date:  2013-02-21       Impact factor: 3.906

8.  The redox state of cytochrome c modulates resistance to methotrexate in human MCF7 breast cancer cells.

Authors:  Susana Barros; Núria Mencia; Laura Rodríguez; Carlota Oleaga; Conceição Santos; Verónique Noé; Carlos J Ciudad
Journal:  PLoS One       Date:  2013-05-13       Impact factor: 3.240
  8 in total

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