Literature DB >> 18289060

Apolipoprotein E knockout models.

Genovefa Kolovou1, Katherine Anagnostopoulou, Dimitri P Mikhailidis, Dennis V Cokkinos.   

Abstract

Atherosclerosis is a multifactorial and long-lasting process in humans. Therefore, animal models where more rapid changes occur can be useful for the study of this process. Among such models are the apolipoprotein (apo) E knock out mice. Apo E deficient mice show impaired clearing of plasma lipoproteins and they develop atherosclerosis in a short time. The current review considers lipid metabolism and inflammation as well as nutritional and pharmacological agents affecting atherosclerosis, using the apo E knock out mouse model.

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Year:  2008        PMID： 18289060     DOI： 10.2174/138161208783497769

Source DB:  PubMed          Journal:  Curr Pharm Des        ISSN： 1381-6128            Impact factor:   3.116


  28 in total

Review 1.  Vascular complications of cystathionine β-synthase deficiency: future directions for homocysteine-to-hydrogen sulfide research.

Authors:  Richard S Beard; Shawn E Bearden
Journal:  Am J Physiol Heart Circ Physiol       Date:  2010-10-22       Impact factor: 4.733

2.  Apolipoprotein E favours the blunting by high-fat diet of prostacyclin receptor activation in the mouse aorta.

Authors:  Yanhua Cheng; Paul M Vanhoutte; Susan W S Leung
Journal:  Br J Pharmacol       Date:  2018-07-22       Impact factor: 8.739

3.  Lipoproteins and lipoprotein metabolism in periodontal disease.

Authors:  Rachel Griffiths; Suzanne Barbour
Journal:  Clin Lipidol       Date:  2010-06

4.  Telmisartan, ramipril and their combination improve endothelial function in different tissues in a murine model of cholesterol-induced atherosclerosis.

Authors:  N Schlimmer; M Kratz; M Böhm; M Baumhäkel
Journal:  Br J Pharmacol       Date:  2011-06       Impact factor: 8.739

Review 5.  Cardiovascular Diseases and Periodontitis.

Authors:  Peter Riis Hansen; Palle Holmstrup
Journal:  Adv Exp Med Biol       Date:  2022       Impact factor: 2.622

6.  Hydrogen-rich water decreases serum LDL-cholesterol levels and improves HDL function in patients with potential metabolic syndrome.

Authors:  Guohua Song; Min Li; Hui Sang; Liying Zhang; Xiuhong Li; Shutong Yao; Yang Yu; Chuanlong Zong; Yazhuo Xue; Shucun Qin
Journal:  J Lipid Res       Date:  2013-04-22       Impact factor: 5.922

7.  Nicotinic acid and DP1 blockade: studies in mouse models of atherosclerosis.

Authors:  Alison M Strack; Ester Carballo-Jane; Sheng-Ping Wang; Jiyan Xue; Xiaoli Ping; Lesley Ann McNamara; Anil Thankappan; Olga Price; Michael Wolff; T J Wu; Douglas Kawka; Michele Mariano; Charlotte Burton; Ching H Chang; Jing Chen; John Menke; Silvi Luell; Emanuel I Zycband; Xinchun Tong; Richard Raubertas; Carl P Sparrow; Brian Hubbard; John Woods; Gary O'Neill; M Gerard Waters; Ayesha Sitlani
Journal:  J Lipid Res       Date:  2012-10-28       Impact factor: 5.922

8.  Hyperlipidemia modifies innate immune responses to lipopolysaccharide via the TLR-NF-κB signaling pathway.

Authors:  Shuai Chen; Gengbing Lin; Lang Lei; Xiaoqing You; Chunfang Wu; Wenjing Xu; Min Huang; Lan Luo; Zhijun Wang; Yanfen Li; Xin Zhao; Fuhua Yan
Journal:  Inflammation       Date:  2013-08       Impact factor: 4.092

9.  Bioavailability and molecular activities of anthocyanins as modulators of endothelial function.

Authors:  Antonio Speciale; Francesco Cimino; Antonella Saija; Raffaella Canali; Fabio Virgili
Journal:  Genes Nutr       Date:  2014-05-17       Impact factor: 5.523

10.  Functionalization of gadolinium metallofullerenes for detecting atherosclerotic plaque lesions by cardiovascular magnetic resonance.

Authors:  Anthony Dellinger; John Olson; Kerry Link; Stephen Vance; Marinella G Sandros; Jijin Yang; Zhiguo Zhou; Christopher L Kepley
Journal:  J Cardiovasc Magn Reson       Date:  2013-01-16       Impact factor: 5.364
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