Literature DB >> 18287783

Open-source platform for the analysis of liquid chromatography-mass spectrometry (LC-MS) data.

Matthew Fitzgibbon1, Wendy Law, Damon May, Andrea Detter, Martin McIntosh.   

Abstract

The analysis of protein mixtures by liquid chromatography-mass spectrometry (LCMS) requires tools for viewing and navigating LC-MS data, locating peptides in LC-MS data, and eliminating low-quality peptides. msInspect, an open source platform, can carry out these steps for single experiments and can align and normalize peptide features in comparative studies with multiple LC-MS runs. In addition, msInspect can analyze quantitative studies with and without isotopic labels to generate peptide arrays.

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Year:  2008        PMID: 18287783     DOI: 10.1007/978-1-59745-117-8_19

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  3 in total

Review 1.  Proteomics and the analysis of proteomic data: 2013 overview of current protein-profiling technologies.

Authors:  Can Bruce; Kathryn Stone; Erol Gulcicek; Kenneth Williams
Journal:  Curr Protoc Bioinformatics       Date:  2013-03

2.  Post analysis data acquisition for the iterative MS/MS sampling of proteomics mixtures.

Authors:  Michael R Hoopmann; Gennifer E Merrihew; Priska D von Haller; Michael J MacCoss
Journal:  J Proteome Res       Date:  2009-04       Impact factor: 4.466

3.  'Brukin2D': a 2D visualization and comparison tool for LC-MS data.

Authors:  Dimosthenis Tsagkrasoulis; Panagiotis Zerefos; George Loudos; Antonia Vlahou; Marc Baumann; Sophia Kossida
Journal:  BMC Bioinformatics       Date:  2009-06-16       Impact factor: 3.169

  3 in total

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