PURPOSE OF REVIEW: Perceptions of the utility of cardiovascular magnetic resonance in the evaluation of arrhythmogenic right ventricular cardiomyopathy have changed considerably in the past decade. This review offers an up-to-date perspective on the diagnostic role of cardiovascular magnetic resonance in the genetics era. RECENT FINDINGS: Originally hailed as a putative gold standard in arrhythmogenic cardiomyopathy, cardiovascular magnetic resonance has received a more guarded reception lately owing to interobserver variability and lack of standardized protocols. Recent studies have nonetheless affirmed its value as an integral component of the diagnostic work-up. Quantitative volume analysis is relatively robust, but visualization of myocardial fat by spin-echo imaging is less reliable. Interpretation of wall motion abnormalities appears reproducible among expert readers. Emerging data suggest a key role for late gadolinium enhancement in detection of left ventricular involvement. SUMMARY: Cardiovascular magnetic resonance in arrhythmogenic cardiomyopathy is facilitated by appropriate patient selection and preparation, experienced readers and operators, and a dedicated, comprehensive protocol. Indications for magnetic resonance assessment include proven arrhythmogenic cardiomyopathy in the family, unexplained ventricular arrhythmia, inverted T-waves in the right precordial or lateral leads, and/or family history of sudden cardiac death. Arrhythmia suppression is essential for optimal electrocardiographic triggering and image acquisition.
PURPOSE OF REVIEW: Perceptions of the utility of cardiovascular magnetic resonance in the evaluation of arrhythmogenic right ventricular cardiomyopathy have changed considerably in the past decade. This review offers an up-to-date perspective on the diagnostic role of cardiovascular magnetic resonance in the genetics era. RECENT FINDINGS: Originally hailed as a putative gold standard in arrhythmogenic cardiomyopathy, cardiovascular magnetic resonance has received a more guarded reception lately owing to interobserver variability and lack of standardized protocols. Recent studies have nonetheless affirmed its value as an integral component of the diagnostic work-up. Quantitative volume analysis is relatively robust, but visualization of myocardial fat by spin-echo imaging is less reliable. Interpretation of wall motion abnormalities appears reproducible among expert readers. Emerging data suggest a key role for late gadolinium enhancement in detection of left ventricular involvement. SUMMARY: Cardiovascular magnetic resonance in arrhythmogenic cardiomyopathy is facilitated by appropriate patient selection and preparation, experienced readers and operators, and a dedicated, comprehensive protocol. Indications for magnetic resonance assessment include proven arrhythmogenic cardiomyopathy in the family, unexplained ventricular arrhythmia, inverted T-waves in the right precordial or lateral leads, and/or family history of sudden cardiac death. Arrhythmia suppression is essential for optimal electrocardiographic triggering and image acquisition.
Authors: Anneline S J M te Riele; Aditya Bhonsale; Cynthia A James; Neda Rastegar; Brittney Murray; Jeremy R Burt; Crystal Tichnell; Srinivasa Madhavan; Daniel P Judge; David A Bluemke; Stefan L Zimmerman; Ihab R Kamel; Hugh Calkins; Harikrishna Tandri Journal: J Am Coll Cardiol Date: 2013-06-27 Impact factor: 24.094