| Literature DB >> 18281216 |
Andreas J Steiner1, Arnold E Stütz, Tanja M Wrodnigg, Chris A Tarling, Stephen G Withers, Albin Hermetter, Hannes Schmidinger.
Abstract
Three typical glycosidase-inhibiting iminoalditols were attached to a polyamine surface displayed on a silicon chip. Exposure to a representative beta-glucosidase revealed selective binding events reflecting the different structural features of the inhibitors probed in this study. This provides a proof-of-concept for the successful exploitation of microarrays of typical reversible glycosidase inhibitors of the iminosugar family.Entities:
Mesh：
Substances：
Year: 2008 PMID： 18281216 DOI： 10.1016/j.bmcl.2008.01.124
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823