Literature DB >> 18281131

Does a novel prefilled injection device make postpartum oxytocin easier to administer? Results from midwives in Vietnam.

Vivien D Tsu1, Huong T T Luu, Tran T P Mai.   

Abstract

OBJECTIVE: to assess the acceptability of the Uniject prefilled injection device for delivery of oxytocin in the third stage of labour, and the effect of the device on overall willingness to perform active management of the third stage of labour (AMTSL).
DESIGN: descriptive study that used baseline and post-intervention questionnaires.
SETTING: three districts in northern Vietnam. The study population consisted of 52 midwives from two districts where AMTSL was already practiced, and 35 midwives from a district where AMTSL was introduced as part of the study. MEASUREMENTS AND
FINDINGS: the majority of midwives reported that the Uniject device was easier to use and preferable compared with ampoules and standard syringes. They found the training materials easy to understand. KEY
CONCLUSIONS: the use of a prefilled injection device overcame many of the barriers cited by midwives with regard to the use of oxytocin in ampoules, such as trying to break ampoules and fill syringes in a hurry. This device enabled midwives to deliver the correct dose of oxytocin in the third stage of labour in a safe and timely way, while attending to the other needs of the mother and her newborn baby. IMPLICATIONS FOR PRACTICE: use of a prefilled injection device for oxytocin may increase the acceptability and practice of AMTSL in primary level facilities, thus reducing maternal mortality due to postpartum haemorrhage.

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Year:  2008        PMID: 18281131     DOI: 10.1016/j.midw.2007.10.010

Source DB:  PubMed          Journal:  Midwifery        ISSN: 0266-6138            Impact factor:   2.372


  12 in total

Review 1.  Prostaglandins for preventing postpartum haemorrhage.

Authors:  Özge Tunçalp; G Justus Hofmeyr; A Metin Gülmezoglu
Journal:  Cochrane Database Syst Rev       Date:  2012-08-15

2.  Intravenous versus intramuscular prophylactic oxytocin for the third stage of labour.

Authors:  Olufemi T Oladapo; Babasola O Okusanya; Edgardo Abalos; Ioannis D Gallos; Argyro Papadopoulou
Journal:  Cochrane Database Syst Rev       Date:  2020-11-09

3.  Impact on postpartum hemorrhage of prophylactic administration of oxytocin 10 IU via Uniject™ by peripheral health care providers at home births: design of a community-based cluster-randomized trial.

Authors:  Cynthia K Stanton; Samuel Newton; Luke C Mullany; Patience Cofie; Charlotte Tawiah Agyemang; Edward Adiibokah; Niamh Darcy; Sadaf Khan; Alice Levisay; John Gyapong; Deborah Armbruster; Seth Owusu-Agyei
Journal:  BMC Pregnancy Childbirth       Date:  2012-06-07       Impact factor: 3.007

4.  Bedside Availability of Prepared Oxytocin and Rapid Administration After Delivery to Prevent Postpartum Hemorrhage: An Observational Study in Karnataka, India.

Authors:  Corrina Moucheraud; Jonathon Gass; Stuart Lipsitz; Jonathan Spector; Priya Agrawal; Lisa R Hirschhorn; Atul Gawande; Bhala Kodkany
Journal:  Glob Health Sci Pract       Date:  2015-06-17

5.  Oxytocin in Uniject Disposable Auto-Disable Injection System versus Standard Use for the Prevention of Postpartum Hemorrhage in Latin America and the Caribbean: A Cost-Effectiveness Analysis.

Authors:  Andrés Pichon-Riviere; Demián Glujovsky; Osvaldo Ulises Garay; Federico Augustovski; Agustin Ciapponi; Magdalena Serpa; Fernando Althabe
Journal:  PLoS One       Date:  2015-06-09       Impact factor: 3.240

6.  Local markets for global health technologies: lessons learned from advancing 6 new products.

Authors:  Dipika Mathur Matthias; Catharine H Taylor; Debjeet Sen; Mutsumi Metzler
Journal:  Glob Health Sci Pract       Date:  2014-05-13

7.  Can a Compact Pre-Filled Auto-Disable Injection System (cPAD) Save Costs for DTP-HepB-Hib Vaccine as Compared with Single-Dose (SDV) and Multi-Dose Vials (MDV)? Evidence from Cambodia, Ghana, and Peru.

Authors:  Cyril Nogier; Patrick Hanlon; Karin Wiedenmayer; Nicolas Maire
Journal:  Drugs Real World Outcomes       Date:  2015-03

Review 8.  Intramuscular versus intravenous prophylactic oxytocin for the third stage of labour.

Authors:  Olufemi T Oladapo; Babasola O Okusanya; Edgardo Abalos
Journal:  Cochrane Database Syst Rev       Date:  2018-09-22

9.  Effect on postpartum hemorrhage of prophylactic oxytocin (10 IU) by injection by community health officers in Ghana: a community-based, cluster-randomized trial.

Authors:  Cynthia K Stanton; Samuel Newton; Luke C Mullany; Patience Cofie; Charlotte Tawiah Agyemang; Edward Adiibokah; Seeba Amenga-Etego; Niamh Darcy; Sadaf Khan; Deborah Armbruster; John Gyapong; Seth Owusu-Agyei
Journal:  PLoS Med       Date:  2013-10-01       Impact factor: 11.069

10.  Pulmonary delivery of an ultra-fine oxytocin dry powder formulation: potential for treatment of postpartum haemorrhage in developing countries.

Authors:  Richard J Prankerd; Tri-Hung Nguyen; Jibriil P Ibrahim; Robert J Bischof; Gemma C Nassta; Livesey D Olerile; Adrian S Russell; Felix Meiser; Helena C Parkington; Harold A Coleman; David A V Morton; Michelle P McIntosh
Journal:  PLoS One       Date:  2013-12-23       Impact factor: 3.240

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