Literature DB >> 18281036

Premature ovarian failure and androgen receptor gene CAG repeat lengths weighted by X chromosome inactivation patterns.

Fumihiro Sugawa1, Yuka Wada, Tetsuo Maruyama, Hiroshi Uchida, Bunpei Ishizuka, Tsutomu Ogata.   

Abstract

The CAG repeat lengths weighted by X-inactivation ratios were significantly shorter in 58 Japanese patients with premature ovarian failure (POF) than in 42 age-matched control females with normal menses. The results suggest that short CAG repeats with a relatively high androgen receptor function may constitute a susceptibility factor for the development of POF.

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Year:  2008        PMID: 18281036     DOI: 10.1016/j.fertnstert.2007.11.085

Source DB:  PubMed          Journal:  Fertil Steril        ISSN: 0015-0282            Impact factor:   7.329


  3 in total

1.  The role of genetic and autoimmune factors in premature ovarian failure.

Authors:  Nigyar N Shamilova; Larisa A Marchenko; Nataliya V Dolgushina; Dmitry V Zaletaev; Gennady T Sukhikh
Journal:  J Assist Reprod Genet       Date:  2013-03-16       Impact factor: 3.412

Review 2.  Genetics of primary ovarian insufficiency: new developments and opportunities.

Authors:  Yingying Qin; Xue Jiao; Joe Leigh Simpson; Zi-Jiang Chen
Journal:  Hum Reprod Update       Date:  2015-08-04       Impact factor: 15.610

3.  Associations between androgen receptor CAG & GGN repeat polymorphism & recurrent spontaneous abortions in Chinese women.

Authors:  Zhang Chuan; Dang Jie; Xu Hao; Bao Junhua; Guo Mengjing; Pei Liguo; Yan Yousheng; Lu Hong; Huo Zhenghao
Journal:  Indian J Med Res       Date:  2014-05       Impact factor: 2.375

  3 in total

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