Literature DB >> 18280000

The function of serotonin within the liver.

Richard G Ruddell1, Derek A Mann, Grant A Ramm.   

Abstract

Serotonin or 5-hydroxytryptamine (5-HT) is known to regulate several key aspects of liver biology and these functions include hepatic blood flow, innervation and wound healing. Given the importance of these functions it is surprising that relatively little time has been dedicated to studying the precise function and mechanisms of serotonin within the liver. Here we describe what is known about serotonin and the liver and those receptor types that mediate the observed effects with an aim to stimulating new interest in the field of serotonin and liver biology.

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Year:  2008        PMID: 18280000     DOI: 10.1016/j.jhep.2008.01.006

Source DB:  PubMed          Journal:  J Hepatol        ISSN: 0168-8278            Impact factor:   25.083


  39 in total

1.  Paracrine modulation of cholangiocyte serotonin synthesis orchestrates biliary remodeling in adults.

Authors:  Alessia Omenetti; Liu Yang; Raul R Gainetdinov; Cynthia D Guy; Steve S Choi; Wei Chen; Marc G Caron; Anna Mae Diehl
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2010-11-11       Impact factor: 4.052

2.  Role of serotonin in development of esophageal and gastric fundal varices.

Authors:  Jelena S Rudić; Dorđe M Culafić; Duško S Mirković; Rada S Ješić; Miodrag N Krstić
Journal:  World J Gastroenterol       Date:  2010-12-28       Impact factor: 5.742

3.  Biogenic amines serotonin and dopamine regulate cholangiocyte hyperplastic and neoplastic growth.

Authors:  Gabriel A Frampton; Huang Li; Jonathan Ramirez; Akimuddin Mohamad; Sharon Demorrow
Journal:  World J Gastrointest Pathophysiol       Date:  2010-06-15

4.  Modulation of the Tryptophan Hydroxylase 1/Monoamine Oxidase-A/5-Hydroxytryptamine/5-Hydroxytryptamine Receptor 2A/2B/2C Axis Regulates Biliary Proliferation and Liver Fibrosis During Cholestasis.

Authors:  Konstantina Kyritsi; Lixian Chen; April O'Brien; Heather Francis; Travis W Hein; Julie Venter; Nan Wu; Ludovica Ceci; Tianhao Zhou; David Zawieja; Anatoliy A Gashev; Fanyin Meng; Pietro Invernizzi; Luca Fabris; Chaodong Wu; Nicholas J Skill; Romil Saxena; Suthat Liangpunsakul; Gianfranco Alpini; Shannon S Glaser
Journal:  Hepatology       Date:  2019-10-18       Impact factor: 17.425

5.  Serotonin and the 5-HT7 receptor: the link between hepatocytes, IGF-1 and small intestinal neuroendocrine tumors.

Authors:  Bernhard Svejda; Mark Kidd; Andrew Timberlake; Kathy Harry; Alexander Kazberouk; Simon Schimmack; Ben Lawrence; Roswitha Pfragner; Irvin M Modlin
Journal:  Cancer Sci       Date:  2013-05-24       Impact factor: 6.716

Review 6.  Chronic inflammation, immune escape, and oncogenesis in the liver: a unique neighborhood for novel intersections.

Authors:  Jimmy K Stauffer; Anthony J Scarzello; Qun Jiang; Robert H Wiltrout
Journal:  Hepatology       Date:  2012-09-11       Impact factor: 17.425

7.  5-Hydroxytryptamine promotes hepatocellular carcinoma proliferation by influencing β-catenin.

Authors:  Sarwat Fatima; Xiaoke Shi; Zesi Lin; Guo-qing Chen; Xiao-hua Pan; Justin Che-Yuen Wu; John W Ho; Nikki P Lee; Hengjun Gao; Ge Zhang; Aiping Lu; Zhao Xiang Bian
Journal:  Mol Oncol       Date:  2015-09-30       Impact factor: 6.603

8.  Hepatic mosaic enhancement pattern correlates with increased inflammatory activity and adverse therapeutic outcomes in patients with Crohn's disease.

Authors:  Li Shi; Bao-Lan Lu; Yun Qiu; Li Huang; Si-Yun Huang; Ren Mao; Jin-Jiang Lin; Jin-Fang Du; Shi-Ting Feng; Zi-Ping Li; Can-Hui Sun; Xue-Hua Li
Journal:  Abdom Radiol (NY)       Date:  2021-03-01

9.  A cell protection screen reveals potent inhibitors of multiple stages of the hepatitis C virus life cycle.

Authors:  Karuppiah Chockalingam; Rudo L Simeon; Charles M Rice; Zhilei Chen
Journal:  Proc Natl Acad Sci U S A       Date:  2010-02-08       Impact factor: 11.205

10.  Ondansetron attenuates depression co-morbid with obesity in obese mice subjected to chronic unpredictable mild stress; an approach using behavioral battery tests.

Authors:  Yeshwant Kurhe; Mahesh Radhakrishnan; Deepali Gupta
Journal:  Metab Brain Dis       Date:  2014-06-27       Impact factor: 3.584

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