Literature DB >> 18278284

[Serology as a diagnostic tool for surveillance and control of schistosomiasis in Holambra, São Paulo State, Brazil].

Cybele Gargioni1, Rita Maria da Silva, Célia Maria Thomé, Celma Maria da Silva Quadros, Hermínia Yohko Kanamura.   

Abstract

The present study aimed to evaluate the incorporation of the immunofluorescence test (IFT) with adult parasite paraffin sections as antigen substrate for the detection of IgM antibodies (IgM-IFT), as a diagnostic method in the schistosomiasis control program in the county (municipality) of Holambra, São Paulo State, Brazil. This city was selected for this study based on its low endemicity for schistosomiasis, the first cases having been reported in 1993, and because of the need to implement a control program with more sensitive diagnostic techniques. 202 individuals underwent IgM-IFT, with 48 serologically positive cases; of these, 28 were tested with the Kato-Katz technique, using three stool samples. Schistosoma mansoni eggs were found in 14 individuals, with egg counts varying from 2.7 to 224 per gram of stool. The results indicate the potential usefulness of IgM-IFT as a screening test, subject to subsequent confirmation using a parasitological method, in low-endemic areas for schistosomiasis.

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Year:  2008        PMID: 18278284     DOI: 10.1590/s0102-311x2008000200016

Source DB:  PubMed          Journal:  Cad Saude Publica        ISSN: 0102-311X            Impact factor:   1.632


  1 in total

Review 1.  Immunodiagnostic methods: what is their role in areas of low endemicity?

Authors:  Rafaella Fortini Queiroz Grenfell; Vanessa Silva-Moraes; Diana Taboada; Ana Carolina Alves de Mattos; Ana Karine Sarvel de Castro; Paulo Marcos Zech Coelho
Journal:  ScientificWorldJournal       Date:  2012-12-17
  1 in total

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