| Literature DB >> 18278271 |
Adriano Pinter1, Maurício C Horta, Richard C Pacheco, Jonas Moraes-Filho, Marcelo B Labruna.
Abstract
The present study provides a rickettsial serosurvey in 25 dogs and 35 humans in an endemic area for Brazilian spotted fever in the State of São Paulo, where the tick Amblyomma aureolatum is the main vector. Testing canine and human sera by indirect immunofluorescence against four Rickettsia antigens (R. rickettsii, R. parkeri, R. felis and R. bellii) showed that 16 (64%) of canine sera and 1 (2.8%) of human sera reacted to at least one of these rickettsial antigens with titers >0r= 64. Seven canine sera and the single reactive human serum showed titers to R. rickettsii at least four times those of any of the other three antigens. The antibody titers in these 7 animals and 1 human were attributed to stimulation by R. rickettsii infection. No positive canine or human serum was attributed to stimulation by R. parkeri, R. felis, or R. bellii. Our serological results showed that dogs are important sentinels for the presence of R. rickettsii in areas where the tick A. aureolatum is the main vector of Brazilian spotted fever.Entities:
Mesh：
Substances：
Year: 2008 PMID： 18278271 DOI： 10.1590/s0102-311x2008000200003
Source DB: PubMed Journal: Cad Saude Publica ISSN： 0102-311X Impact factor: 1.632