Literature DB >> 18277862

Outcomes of posterior spinal fusion and instrumentation in patients with continuous intrathecal baclofen infusion pumps.

Michelle S Caird1, Ariel A Palanca, Hugh Garton, Robert N Hensinger, Rita N Ayyangar, Amy Drongowski, Frances A Farley.   

Abstract

STUDY
DESIGN: In this retrospective study, 20 spastic quadriplegic cerebral palsy (CP) patients with baclofen pumps, who underwent spinal fusion and instrumentation for neuromuscular scoliosis, were matched for weight, age, and type of fusion with patients without pumps.
OBJECTIVE: The objective of this study is to determine the rate of complications, adverse outcomes, and curve correction after spinal fusion in patients with CP and baclofen pumps compared with similar patients without pumps. SUMMARY OF BACKGROUND DATA: CP patients treated with continuous intrathecal baclofen (ITB) can develop neuromuscular scoliosis and may require spinal fusion with instrumentation. ITB pumps may increase complications with this procedure.
METHODS: Medical records were examined, and preoperative risks, intraoperative complications, postoperative complications, and pump-specific complications were documented. Cobb angles were measured throughout the treatment to determine surgical correction.
RESULTS: Pump patients more frequently required reoperation (9 vs. 4, P = 0.039) and rehospitalization (8 vs. 2, P = 0.008). There was a trend toward more wound infections in pump patients (5 vs. 0, P = 0.063). Nine pump patients (45%) had a pump-related complication; 5 of these patients required pump removal or revision. Complications included durotomy, tubing problems, and deep spinal infection. Average surgical correction in pump patients was 42% (81 degrees -48 degrees ) versus 50% (81 degrees -39 degrees ) in nonpump patients, with no significant difference between pairs (P = 0.11).
CONCLUSION: CP patients with baclofen pumps who underwent spinal fusion had more complications compared with similar patients without pumps. There was no significant difference in surgical correction between matched pairs. Physicians and families should be aware of the increased risks of reoperation and rehospitalization after spinal fusion in the presence of baclofen pumps.

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Year:  2008        PMID: 18277862     DOI: 10.1097/BRS.0b013e3181642aae

Source DB:  PubMed          Journal:  Spine (Phila Pa 1976)        ISSN: 0362-2436            Impact factor:   3.468


  6 in total

1.  Expert's comment concerning Grand Rounds case entitled "Combined selective dorsal rhizotomy and scoliosis correction procedure in patients with cerebral palsy" (Samiul Muquit, Amr Ammar, Luigi Nasto, Ahmad A. Moussa, Hossein Mehdian, Michael H. Vloeberghs).

Authors:  D Kojo Hamilton
Journal:  Eur Spine J       Date:  2015-09-07       Impact factor: 3.134

Review 2.  The management of scoliosis in children with cerebral palsy: a review.

Authors:  Thomas Cloake; Adrian Gardner
Journal:  J Spine Surg       Date:  2016-12

3.  Intrathecal baclofen pumps do not accelerate progression of scoliosis in quadriplegic spastic cerebral palsy.

Authors:  Paul R P Rushton; Luigi A Nasto; Ranjit K Aujla; Amr Ammar; Michael P Grevitt; Michael H Vloeberghs
Journal:  Eur Spine J       Date:  2016-05-06       Impact factor: 3.134

Review 4.  Infections after spinal correction and fusion for spinal deformities in childhood and adolescence.

Authors:  Manon Bachy; Benjamin Bouyer; Raphaël Vialle
Journal:  Int Orthop       Date:  2011-12-11       Impact factor: 3.075

5.  Surgical correction of scoliosis in children with spastic quadriplegia: benefits, adverse effects, and patient selection.

Authors:  Julian Legg; Evan Davies; Annie L Raich; Joseph R Dettori; Ned Sherry
Journal:  Evid Based Spine Care J       Date:  2014-04

Review 6.  Intrathecal baclofen for treating spasticity in children with cerebral palsy.

Authors:  Monika J Hasnat; James E Rice
Journal:  Cochrane Database Syst Rev       Date:  2015-11-13
  6 in total

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