BACKGROUND: Using more than one therapeutic approach in the treatment of basal cell carcinomas (BCCs) has the potential to enhance cure rates. MATERIALS AND METHODS: In this study, 57 nodular and superficial BCCs were curetted without electrodesiccation. One week later, imiquimod 5% cream therapy was initiated once daily 5 times per week for 6 weeks. At 1-year follow-up, 0 of 57 BCCs (0%) had clinical recurrences. Cosmetic results were very good to excellent. CONCLUSION: Combination therapy with imiquimod 5% cream followed by curettage represents an effective method for treating BCCs with a high cure rate.
BACKGROUND: Using more than one therapeutic approach in the treatment of basal cell carcinomas (BCCs) has the potential to enhance cure rates. MATERIALS AND METHODS: In this study, 57 nodular and superficial BCCs were curetted without electrodesiccation. One week later, imiquimod 5% cream therapy was initiated once daily 5 times per week for 6 weeks. At 1-year follow-up, 0 of 57 BCCs (0%) had clinical recurrences. Cosmetic results were very good to excellent. CONCLUSION: Combination therapy with imiquimod 5% cream followed by curettage represents an effective method for treating BCCs with a high cure rate.
Authors: P Severino; J F Fangueiro; S V Ferreira; R Basso; M V Chaud; M H A Santana; A Rosmaninho; E B Souto Journal: Clin Transl Oncol Date: 2013-01-24 Impact factor: 3.405