Literature DB >> 18277170

Emerging technology in molecular epidemiology: what epidemiologists need to know.

Frederica P Perera1, Julie B Herbstman.   

Abstract

Epidemiology has evolved with the development of new molecular technologies that refine the way we investigate the relationships between exposure and disease. While these novel tools open new opportunities to delve into the mechanisms of the molecular epidemiologic continuum, they also come with the challenge of ensuring their meaningful application in epidemiologic investigations. To train successful molecular epidemiologists in the postgenome/epigenome era, we can look to the "lessons learned" when epidemiologists first integrated molecular biomarkers into traditional epidemiologic designs. These examples show how interdisciplinary training in molecular epidemiology programs can help ensure that new technologies are used effectively to understand the mechanisms driving exposure-disease relationships.

Mesh:

Substances:

Year:  2008        PMID: 18277170      PMCID: PMC3171167          DOI: 10.1097/EDE.0b013e318162a920

Source DB:  PubMed          Journal:  Epidemiology        ISSN: 1044-3983            Impact factor:   4.822


  13 in total

Review 1.  The history of cancer epigenetics.

Authors:  Andrew P Feinberg; Benjamin Tycko
Journal:  Nat Rev Cancer       Date:  2004-02       Impact factor: 60.716

2.  A pilot project in molecular cancer epidemiology: determination of benzo[a]pyrene--DNA adducts in animal and human tissues by immunoassays.

Authors:  F P Perera; M C Poirier; S H Yuspa; J Nakayama; A Jaretzki; M M Curnen; D M Knowles; I B Weinstein
Journal:  Carcinogenesis       Date:  1982       Impact factor: 4.944

3.  Molecular epidemiology and carcinogen-DNA adduct detection: new approaches to studies of human cancer causation.

Authors:  F P Perera; I B Weinstein
Journal:  J Chronic Dis       Date:  1982

4.  Variability in PAH-DNA adduct measurements in peripheral mononuclear cells: implications for quantitative cancer risk assessment.

Authors:  C Dickey; R M Santella; D Hattis; D Tang; Y Hsu; T Cooper; T L Young; F P Perera
Journal:  Risk Anal       Date:  1997-10       Impact factor: 4.000

Review 5.  Bulky DNA adducts and risk of cancer: a meta-analysis.

Authors:  Fabrizio Veglia; Giuseppe Matullo; Paolo Vineis
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2003-02       Impact factor: 4.254

Review 6.  Application of new techniques for the detection of carcinogen adducts to human population monitoring.

Authors:  R M Santella
Journal:  Mutat Res       Date:  1988 May-Aug       Impact factor: 2.433

Review 7.  Mechanisms of chemical carcinogenesis.

Authors:  E C Miller; J A Miller
Journal:  Cancer       Date:  1981-03-01       Impact factor: 6.860

8.  A molecular epidemiological case-control study of lung cancer.

Authors:  D Tang; R M Santella; A M Blackwood; T L Young; J Mayer; A Jaretzki; S Grantham; W Y Tsai; F P Perera
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  1995-06       Impact factor: 4.254

Review 9.  Cancer risk assessment, indicators, and guidelines for polycyclic aromatic hydrocarbons in the ambient air.

Authors:  Carl-Elis Boström; Per Gerde; Annika Hanberg; Bengt Jernström; Christer Johansson; Titus Kyrklund; Agneta Rannug; Margareta Törnqvist; Katarina Victorin; Roger Westerholm
Journal:  Environ Health Perspect       Date:  2002-06       Impact factor: 9.031

10.  Human epigenome project--up and running.

Authors:  Jane Bradbury
Journal:  PLoS Biol       Date:  2003-12-22       Impact factor: 8.029

View more
  2 in total

1.  Fish oil metabolites: translating promising findings from bench to bedside to reduce cardiovascular disease.

Authors:  P Calderon Artero; C Champagne; S Garigen; Sa Mousa; Rc Block
Journal:  J Glycomics Lipidomics       Date:  2012-02-27

2.  How to make epidemiological training infectious.

Authors:  Steve E Bellan; Juliet R C Pulliam; James C Scott; Jonathan Dushoff
Journal:  PLoS Biol       Date:  2012-04-03       Impact factor: 8.029

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.