Literature DB >> 18275914

Plant-derived compounds in clinical trials.

Arvind Saklani1, Samuel K Kutty.   

Abstract

Plants remain an important source of new drugs, new drug leads and new chemical entities. The plant-based drug discovery resulted mainly in the development of anticancer and anti-infectious agents and continues to contribute to the new leads in clinical trials. A total of 91 plant-derived compounds in clinical trials as of September 2007 are described in this review. A summary of the plant-based drugs launched during 2000-2006 is given.

Mesh：

Substances：

Year:  2007        PMID： 18275914     DOI： 10.1016/j.drudis.2007.10.010

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN： 1359-6446            Impact factor:   7.851


  93 in total

Review 1.  Herbal medicine as inducers of apoptosis in cancer treatment.

Authors:  Elham Safarzadeh; Siamak Sandoghchian Shotorbani; Behzad Baradaran
Journal:  Adv Pharm Bull       Date:  2014-08-25

2.  In vitro antileishmanial and antitrypanosomal activities of five medicinal plants from Burkina Faso.

Authors:  W R Sawadogo; G Le Douaron; A Maciuk; C Bories; P M Loiseau; B Figadère; I P Guissou; O G Nacoulma
Journal:  Parasitol Res       Date:  2011-10-25       Impact factor: 2.289

3.  Targeting multiple key signaling pathways in melanoma using leelamine.

Authors:  Raghavendra Gowda; SubbaRao V Madhunapantula; Omer F Kuzu; Arati Sharma; Gavin P Robertson
Journal:  Mol Cancer Ther       Date:  2014-03-31       Impact factor: 6.261

4.  Clustered patterns of species origins of nature-derived drugs and clues for future bioprospecting.

Authors:  Feng Zhu; Chu Qin; Lin Tao; Xin Liu; Zhe Shi; Xiaohua Ma; Jia Jia; Ying Tan; Cheng Cui; Jinshun Lin; Chunyan Tan; Yuyang Jiang; Yuzong Chen
Journal:  Proc Natl Acad Sci U S A       Date:  2011-07-18       Impact factor: 11.205

5.  Experimental Validation of Antidiabetic Potential of Cayratia trifolia (L.) Domin: An Indigenous Medicinal Plant.

Authors:  Shahid Iqbal Mohammed; Narendra Subhash Salunkhe; Kishor Sukhlal Vishwakarma; Vijay Laxminarayan Maheshwari
Journal:  Indian J Clin Biochem       Date:  2016-08-03

6.  Advances in Plant-derived Edible Nanoparticle-based lipid Nano-drug Delivery Systems as Therapeutic Nanomedicines.

Authors:  Chunhua Yang; Mingzhen Zhang; Didier Merlin
Journal:  J Mater Chem B       Date:  2018-01-29       Impact factor: 6.331

7.  Capilliposide C derived from Lysimachia capillipes Hemsl inhibits growth of human prostate cancer PC3 cells by targeting caspase and MAPK pathways.

Authors:  Ruyi Li; Leilei Zhang; Lijing Zhang; Dan Chen; Jingkui Tian; Li Cao; Lin Zhang
Journal:  Int Urol Nephrol       Date:  2014-02-20       Impact factor: 2.370

8.  Flavoring extracts of Hemidesmus indicus roots and Vanilla planifolia pods exhibit in vitro acetylcholinesterase inhibitory activities.

Authors:  Anish Kundu; Adinpunya Mitra
Journal:  Plant Foods Hum Nutr       Date:  2013-09       Impact factor: 3.921

9.  Synthesis of unsymmetrical biphenyls as potent cytotoxic agents.

Authors:  Gang Wu; Huan-Fang Guo; Kun Gao; Yi-Nan Liu; Kenneth F Bastow; Susan L Morris-Natschke; Kuo-Hsiung Lee; Lan Xie
Journal:  Bioorg Med Chem Lett       Date:  2008-08-22       Impact factor: 2.823

10.  Automated genome mining for natural products.

Authors:  Michael H T Li; Peter M U Ung; James Zajkowski; Sylvie Garneau-Tsodikova; David H Sherman
Journal:  BMC Bioinformatics       Date:  2009-06-16       Impact factor: 3.169
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.