A M Müller1, E Mayer, R Schumacher, K M Müller, W Kamin. 1. Abteilung für Kinderpathologie,Institut für Pathologie, Universitätsklinikum Bonn, Sigmund-Freud-Strasse 25, 53127, Bonn. annette.mueller@ukb.uni-bonn.de
Abstract
BACKGROUND: Differential diagnosis of infantile pulmonary cysts comprises congenital cystic lesions (including foregut cysts) and pneumatoceles (i.e., pulmonary cysts of acquired, inflammatory or traumatic origin). CASE: We report the resection of a subpleural air-filled lung cyst of 4 cm in a former preterm (33rd week of pregnancy) at the age of 8 months that was first diagnosed 7 days postnatally by chest X-ray. Pneumatocele was diagnosed pathomorphologically. CONCLUSION: In children, most pneumatoceles are caused by trauma or pneumonia. In the case described, disruption of subpleural alveolar walls due to high pressure ventilation is the likely cause. Differential diagnoses are discussed.
BACKGROUND: Differential diagnosis of infantile pulmonary cysts comprises congenital cystic lesions (including foregut cysts) and pneumatoceles (i.e., pulmonary cysts of acquired, inflammatory or traumatic origin). CASE: We report the resection of a subpleural air-filled lung cyst of 4 cm in a former preterm (33rd week of pregnancy) at the age of 8 months that was first diagnosed 7 days postnatally by chest X-ray. Pneumatocele was diagnosed pathomorphologically. CONCLUSION: In children, most pneumatoceles are caused by trauma or pneumonia. In the case described, disruption of subpleural alveolar walls due to high pressure ventilation is the likely cause. Differential diagnoses are discussed.
Authors: Portia A Kreiger; Eduardo D Ruchelli; Soroosh Mahboubi; Holly Hedrick; N Scott Adzick; Pierre A Russo Journal: Am J Surg Pathol Date: 2006-05 Impact factor: 6.394