BACKGROUND: Potential sources of environmental pollution, such as incinerators or landfill sites, can adversely affect reproduction and/or development. Time to pregnancy (TTP) is a validated measure of biological fertility that can be studied with relatively small populations. METHODS: Pregnant local residents living within 3 km of a landfill site ('exposed' group, n = 200) or elsewhere in the Rhondda valleys ('unexposed' group, n = 400) were interviewed by health visitors or midwives. The response rate was 83%. RESULTS: No difference was found in the TTP distributions between the exposed and unexposed groups. Relationships of TTP with covariates were consistent with the literature. CONCLUSIONS: In a context of public and scientific concern about possible reproductive toxicity, an interview study of TTP was highly acceptable to local women. A large enough sample to generate stable TTP distributions was readily achieved.
BACKGROUND: Potential sources of environmental pollution, such as incinerators or landfill sites, can adversely affect reproduction and/or development. Time to pregnancy (TTP) is a validated measure of biological fertility that can be studied with relatively small populations. METHODS: Pregnant local residents living within 3 km of a landfill site ('exposed' group, n = 200) or elsewhere in the Rhondda valleys ('unexposed' group, n = 400) were interviewed by health visitors or midwives. The response rate was 83%. RESULTS: No difference was found in the TTP distributions between the exposed and unexposed groups. Relationships of TTP with covariates were consistent with the literature. CONCLUSIONS: In a context of public and scientific concern about possible reproductive toxicity, an interview study of TTP was highly acceptable to local women. A large enough sample to generate stable TTP distributions was readily achieved.
Authors: Brenda Eskenazi; Marcella Warner; Amy R Marks; Steven Samuels; Larry Needham; Paolo Brambilla; Paolo Mocarelli Journal: Epidemiology Date: 2010-03 Impact factor: 4.822
Authors: M G M Braem; N C Onland-Moret; P A van den Brandt; R A Goldbohm; P H M Peeters; R F P M Kruitwagen; L J Schouten Journal: Am J Epidemiol Date: 2010-09-22 Impact factor: 4.897