Literature DB >> 1827039

Severe hepatocellular dysfunction following cyproterone acetate therapy.

B T Parys1, S Hamid, R G Thomson.   

Abstract

Cyproterone acetate (CPA) is a widely used drug in the treatment of advanced prostatic carcinoma. Although it is generally well tolerated, liver toxicity has been recognised as a complication of long-term use. We report 3 patients with severe hepatocellular damage due to CPA therapy, 2 with fatal fulminant hepatitis.

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Year:  1991        PMID: 1827039     DOI: 10.1111/j.1464-410x.1991.tb15142.x

Source DB:  PubMed          Journal:  Br J Urol        ISSN: 0007-1331


  7 in total

1.  Toxic hepatitis after sequential administration of flutamide and cyproterone acetate.

Authors:  Spilios Manolakopoulos; Sotirios Bethanis; Anastasios Armonis; Michalis Economou; Alec Avgerinos; Dimitrios Tzourmakliotis
Journal:  Dig Dis Sci       Date:  2004-03       Impact factor: 3.199

2.  Hepatic failure induced by cyproterone acetate: A case report and literature review.

Authors:  Jae Heon Kim; Byung Wook Yoo; Won Jae Yang
Journal:  Can Urol Assoc J       Date:  2014-05       Impact factor: 1.862

3.  Pharmacological interventions for those who have sexually offended or are at risk of offending.

Authors:  Omer Khan; Michael Ferriter; Nick Huband; Nadja Smailagic
Journal:  Cochrane Database Syst Rev       Date:  2009

Review 4.  Pharmacological interventions for those who have sexually offended or are at risk of offending.

Authors:  Omer Khan; Michael Ferriter; Nick Huband; Melanie J Powney; Jane A Dennis; Conor Duggan
Journal:  Cochrane Database Syst Rev       Date:  2015-02-18

Review 5.  Fatal fulminant hepatic failure due to cyproterone acetate.

Authors:  G Friedman; E Lamoureux; A H Sherker
Journal:  Dig Dis Sci       Date:  1999-07       Impact factor: 3.199

Review 6.  Hepatotoxicity induced by cyproterone acetate: a report of three cases.

Authors:  Ioanna Savidou; Melanie Deutsch; Aspasia S Soultati; Dimitrios Koudouras; Georgia Kafiri; Spyridon P Dourakis
Journal:  World J Gastroenterol       Date:  2006-12-14       Impact factor: 5.742

Review 7.  Cyproterone. A review of its pharmacology and therapeutic efficacy in prostate cancer.

Authors:  L B Barradell; D Faulds
Journal:  Drugs Aging       Date:  1994-07       Impact factor: 3.923

  7 in total

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