3-D modeling of the thermal coagulation necrosis induced by an interstitial ultrasonic transducer.

This letter describes a temperature-varying attenuation approach for preoperative planning of high intensity ultrasound interstitial targeted therapy. Such approach is mainly aimed at the treatment of primary liver cancer for which a precise lesion control must be achieved. It is shown through simulation that the shape and size of the resulting necrotic volume is significantly different from the one obtained when this tissue property is considered constant in time.