| Literature DB >> 18269288 |
Benjamin Darses1, Andrew E Greene, Susannah C Coote, Jean-François Poisson.
Abstract
An efficient one-pot asymmetric synthesis of cyclobutanones from chiral enol ethers is described. The approach is illustrated with alkyl- and functionalized alkyl-substituted enol ethers (nine examples). A new enantioselective synthesis of cyclobut-G (Lobucavir) could thus be achieved.Entities:
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Year: 2008 PMID： 18269288 DOI： 10.1021/ol702977x
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005