Literature DB >> 18267068

Shared principles in NF-kappaB signaling.

Matthew S Hayden1, Sankar Ghosh.   

Abstract

The transcription factor NF-kappaB has served as a standard for inducible transcription factors for more than 20 years. The numerous stimuli that activate NF-kappaB, and the large number of genes regulated by NF-kappaB, ensure that this transcription factor is still the subject of intense research. Here, we attempt to synthesize some of the basic principles that have emerged from studies of NF-kappaB, and we aim to generate a more unified view of NF-kappaB regulation.

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Year:  2008        PMID: 18267068     DOI: 10.1016/j.cell.2008.01.020

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  1798 in total

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