Literature DB >> 18266816

Phytochemicals for prevention of solar ultraviolet radiation-induced damages.

Vaqar M Adhami1, Deeba N Syed, Naghma Khan, Farrukh Afaq.   

Abstract

While solar light is indispensable for sustenance of life, excessive exposure can cause several skin-related disorders. The UV part of solar radiation, in particular, is linked to disorders ranging from mild inflammatory effects of the skin to as serious as causing several different types of cancers. Changes in lifestyle together with depletion in the atmospheric ozone layer during the last few decades have led to an increase in the incidence of skin cancer. Skin cancers consisting of basal and squamous cell carcinomas are especially linked to the UVB part of solar radiation. Reducing excessive exposure to solar radiation is desirable; however, as this approach is unavoidable, it is suggested that other novel strategies be developed to reduce the effects of solar radiation to skin. One approach to reduce the harmful effects of solar radiation is through the use of phytochemicals, an approach that is popularly known as "Photochemoprotection." In recent years many phytochemicals with potential antioxidant properties have been identified and found to be photoprotective in nature. We describe here some of the most popular phytochemicals being studied that have the potential to reduce the harmful effects associated with solar UV radiation.

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Year:  2008        PMID: 18266816     DOI: 10.1111/j.1751-1097.2007.00293.x

Source DB:  PubMed          Journal:  Photochem Photobiol        ISSN: 0031-8655            Impact factor:   3.421


  21 in total

Review 1.  Polyphenols: skin photoprotection and inhibition of photocarcinogenesis.

Authors:  F Afaq; S K Katiyar
Journal:  Mini Rev Med Chem       Date:  2011-12       Impact factor: 3.862

2.  Temperature-sensitive microemulsion gel: an effective topical delivery system for simultaneous delivery of vitamins C and E.

Authors:  Branka Rozman; Alenka Zvonar; Francoise Falson; Mirjana Gasperlin
Journal:  AAPS PharmSciTech       Date:  2009-01-16       Impact factor: 3.246

3.  Fisetin inhibits growth, induces G₂ /M arrest and apoptosis of human epidermoid carcinoma A431 cells: role of mitochondrial membrane potential disruption and consequent caspases activation.

Authors:  Harish C Pal; Samriti Sharma; Craig A Elmets; Mohammad Athar; Farrukh Afaq
Journal:  Exp Dermatol       Date:  2013-07       Impact factor: 3.960

Review 4.  Prevention of Photocarcinogenesis by Agonists of 5-HT1A and Antagonists of 5-HT2A Receptors.

Authors:  Ana Catarina Menezes; Sara Raposo; Sandra Simões; Helena Ribeiro; Helena Oliveira; Andreia Ascenso
Journal:  Mol Neurobiol       Date:  2015-01-15       Impact factor: 5.590

5.  Pomegranate fruit extract inhibits UVB-induced inflammation and proliferation by modulating NF-κB and MAPK signaling pathways in mouse skin.

Authors:  Naghma Khan; Deeba N Syed; Harish Chandra Pal; Hasan Mukhtar; Farrukh Afaq
Journal:  Photochem Photobiol       Date:  2012-01-13       Impact factor: 3.421

6.  Oral feeding of pomegranate fruit extract inhibits early biomarkers of UVB radiation-induced carcinogenesis in SKH-1 hairless mouse epidermis.

Authors:  Farrukh Afaq; Naghma Khan; Deeba N Syed; Hasan Mukhtar
Journal:  Photochem Photobiol       Date:  2010-10-14       Impact factor: 3.421

7.  Chondracanthus tenellus (Harvey) hommersand extract protects the human keratinocyte cell line by blocking free radicals and UVB radiation-induced cell damage.

Authors:  Mei Jing Piao; Yu Jae Hyun; Tae-Heon Oh; Hee Kyoung Kang; Eun Sook Yoo; Young Sang Koh; Nam Ho Lee; In Soo Suh; Jin Won Hyun
Journal:  In Vitro Cell Dev Biol Anim       Date:  2012-10-24       Impact factor: 2.416

8.  Silibinin inhibits ultraviolet B radiation-induced DNA-damage and apoptosis by enhancing interleukin-12 expression in JB6 cells and SKH-1 hairless mouse skin.

Authors:  Sreekanth Narayanapillai; Chapla Agarwal; Gagan Deep; Rajesh Agarwal
Journal:  Mol Carcinog       Date:  2013-01-28       Impact factor: 4.784

9.  Protective effect of pomegranate-derived products on UVB-mediated damage in human reconstituted skin.

Authors:  Farrukh Afaq; Mohammad Abu Zaid; Naghma Khan; Mark Dreher; Hasan Mukhtar
Journal:  Exp Dermatol       Date:  2009-03-06       Impact factor: 3.960

10.  Fisetin inhibits UVB-induced cutaneous inflammation and activation of PI3K/AKT/NFκB signaling pathways in SKH-1 hairless mice.

Authors:  Harish Chandra Pal; Mohammad Athar; Craig A Elmets; Farrukh Afaq
Journal:  Photochem Photobiol       Date:  2014-10-07       Impact factor: 3.421

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