Literature DB >> 18266379

An efficient synthesis of highly functionalized [5,6] aromatic spiroketals by hetero-Diels-Alder reaction.

Guanglian Zhou1, Jianrong Zhu, Zhixiang Xie, Ying Li.   

Abstract

A hetero-Diels-Alder reaction of vinyl sulfoxides with o-quinone methides precursor constructs highly functionalized [5,6] aromatic spiroketal skeletons in moderate to good yields with high regioselectivity. The two functional groups (ketone and olefin) can be further subjected to many synthetic transformations.

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Year:  2008        PMID: 18266379     DOI: 10.1021/ol7029068

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  1 in total

1.  7-(tert-Butyl-diphenyl-sil-yloxy)-2,2-dimethyl-1-benzofuran-3(2H)-one.

Authors:  Cristian O Salas; Ricardo A Tapia; Alejandro Macías
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2011-01-12
  1 in total

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