Atypical presentation of oral tuberculosis ulcer.

Tuberculosis is a chronic infectious disease that can affect any part of the body, including the mouth. An upsurge in the number of tuberculosis cases, with a strong association with HIV infection, has been noted. We present a case of tuberculosis that clinically resembles a malignant chronic ulcer in the retromolar trigone-an uncommon site of occurrence. Histologically, the case demonstrated an atypical epitheloid granuloma with reduced lymphocyte count. The diagnosis of tuberculosis was confirmed following sputum culture of M tuberculosis. Antitubercular therapy improved the patient's condition. Although rare, tuberculosis must be considered as a differential diagnosis in chronic ulcers in the oral region; and its association with HIV must not be overlooked.