Literature DB >> 18265305

Detection and analysis of proteins modified by O-linked N-acetylglucosamine.

Natasha E Zachara1, Gerald W Hart, Robert N Cole, Yuan Gao.   

Abstract

The modification of Ser and Thr residues with O-linked b-N-acetyl glucosamine (O-GlcNAc) is a common and essential modification of nuclear and cytoplasmic proteins, and it is thought that O-GlcNAc performs a regulatory role in the cell. This unit concentrates on the techniques for the detection and analysis of proteins modified by O-GlcNAc as well as methods for the analysis of enzymes responsible for the addition and removal of this group.

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Year:  2002        PMID： 18265305     DOI： 10.1002/0471142727.mb1706s57

Source DB:  PubMed          Journal:  Curr Protoc Mol Biol        ISSN： 1934-3647


  6 in total

1.  Evidence of the involvement of O-GlcNAc-modified human RNA polymerase II CTD in transcription in vitro and in vivo.

Authors:  Stella M Ranuncolo; Salil Ghosh; John A Hanover; Gerald W Hart; Brian A Lewis
Journal:  J Biol Chem       Date:  2012-05-17       Impact factor: 5.157

Review 2.  Nutrient-driven O-GlcNAc in proteostasis and neurodegeneration.

Authors:  Ilhan Akan; Stephanie Olivier-Van Stichelen; Michelle R Bond; John A Hanover
Journal:  J Neurochem       Date:  2017-11-20       Impact factor: 5.372

3.  Hyperglycemia-induced O-GlcNAcylation and truncation of 4E-BP1 protein in liver of a mouse model of type 1 diabetes.

Authors:  Michael D Dennis; Tabitha L Schrufer; Sarah K Bronson; Scot R Kimball; Leonard S Jefferson
Journal:  J Biol Chem       Date:  2011-08-12       Impact factor: 5.157

4.  A sweet spot in the FGFR signal transduction pathway.

Authors:  Amin S Ghabrial
Journal:  Sci Signal       Date:  2012-01-17       Impact factor: 8.192

5.  Oral benfotiamine plus alpha-lipoic acid normalises complication-causing pathways in type 1 diabetes.

Authors:  X Du; D Edelstein; M Brownlee
Journal:  Diabetologia       Date:  2008-07-29       Impact factor: 10.122

6.  ISPTM: an iterative search algorithm for systematic identification of post-translational modifications from complex proteome mixtures.

Authors:  Xin Huang; Lin Huang; Hong Peng; Ashu Guru; Weihua Xue; Sang Yong Hong; Miao Liu; Seema Sharma; Kai Fu; Adam P Caprez; David R Swanson; Zhixin Zhang; Shi-Jian Ding
Journal:  J Proteome Res       Date:  2013-08-06       Impact factor: 4.466
  6 in total

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