Initiation of lipid autoxidation by ABAP at pH 4-10 in SDS micelles.

The rates of radical generation, R(i), by two water soluble initiators: 2,2'-azobis(2-methylpropionamidine) and 2,2'-azobis[2-methyl-N-(2-hydroxyethyl)propionamide], and the lipid soluble 2,2'-azobisisobutyronitrile were measured in an SDS micellar system over a pH range of 4-10. Enhanced values of R(i) at low pH are attributed to Coulombic repulsion of protonated radicals.