Literature DB >> 18263959

Characterization of an add-on multileaf collimator for electron beam therapy.

T Gauer1, J Sokoll, F Cremers, R Harmansa, M Luzzara, R Schmidt.   

Abstract

An add-on multileaf collimator for electrons (eMLC) has been developed that provides computer-controlled beam collimation and isocentric dose delivery. The design parameters result from the design study by Gauer et al (2006 Phys. Med. Biol. 51 5987-6003) and were configured such that a compact and light-weight eMLC with motorized leaves can be industrially manufactured and stably mounted on a conventional linear accelerator. In the present study, the efficiency of an initial computer-controlled prototype was examined according to the design goals and the performance of energy- and intensity-modulated treatment techniques. This study concentrates on the attachment and gantry stability as well as the dosimetric characteristics of central-axis and off-axis dose, field size dependence, collimator scatter, field abutment, radiation leakage and the setting of the accelerator jaws. To provide isocentric irradiation, the eMLC can be placed either 16 or 28 cm above the isocentre through interchangeable holders. The mechanical implementation of this feature results in a maximum field displacement of less than 0.6 mm at 90 degrees and 270 degrees gantry angles. Compared to a 10 x 10 cm applicator at 6-14 MeV, the beam penumbra of the eMLC at a 16 cm collimator-to-isocentre distance is 0.8-0.4 cm greater and the depth-dose curves show a larger build-up effect. Due to the loss in energy dependence of the therapeutic range and the much lower dose output at small beam sizes, a minimum beam size of 3 x 3 cm is necessary to avoid suboptimal dose delivery. Dose output and beam symmetry are not affected by collimator scatter when the central axis is blocked. As a consequence of the broader beam penumbra, uniform dose distributions were measured in the junction region of adjacent beams at perpendicular and oblique beam incidence. However, adjacent beams with a high difference in a beam energy of 6 to 14 MeV generate cold and hot spots of approximately 15% in the abutting region. In order to improve uniformity, the energy of adjacent beams must be limited to 6 to 10 MeV and 10 to 14 MeV respectively. At the maximum available beam energy of 14 MeV, radiation leakage results mainly from the intraleaf leakage of approximately 2.5% relative dose which could be effectively eliminated at off-axis distances remote from the field edge by adjusting the jaw field size to the respective opening of the eMLC. Additionally, the interleaf and leaf-end leakage could be reduced by using a tongue-and-groove leaf shape and adjoining the leaf-ends off-axis respectively.

Mesh:

Year:  2008        PMID: 18263959     DOI: 10.1088/0031-9155/53/4/017

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  4 in total

1.  Design and evaluation of electron beam energy degraders for breast boost irradiation.

Authors:  Jong In Park; Sung Whan Ha; Jung-In Kim; Hyunseok Lee; Jaegi Lee; Il Han Kim; Sung-Joon Ye
Journal:  Radiat Oncol       Date:  2016-08-31       Impact factor: 3.481

2.  Introduction to passive electron intensity modulation.

Authors:  Kenneth R Hogstrom; Robert L Carver; Erin L Chambers; Kevin Erhart
Journal:  J Appl Clin Med Phys       Date:  2017-09-06       Impact factor: 2.102

3.  A dosimetric comparison of copper and Cerrobend electron inserts.

Authors:  Benjamin D Rusk; Robert L Carver; John P Gibbons; Kenneth R Hogstrom
Journal:  J Appl Clin Med Phys       Date:  2016-09-08       Impact factor: 2.102

4.  Design and production of 3D printed bolus for electron radiation therapy.

Authors:  Shiqin Su; Kathryn Moran; James L Robar
Journal:  J Appl Clin Med Phys       Date:  2014-07-08       Impact factor: 2.102

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.