Literature DB >> 18261170

Selective hemi-portocaval shunt based on portal vein pressure for small-for-size graft in adult living donor liver transplantation.

T Yamada1, K Tanaka, K Uryuhara, K Ito, Y Takada, S Uemoto.   

Abstract

We developed an algorithm of graft selection in which left lobe donation is considered primarily if the graft-to-recipient weight ratio (GRWR) is estimated to be greater than 0.6% in preoperative volumetry with utilization of a hemi-portocaval shunt (HPCS) based on portal vein pressure (PVP) more than 20 mmHg at the time of laparotomy. A total of 11 consecutive adult living donor liver transplantations with small-for-size graft according to our graft selection algorithm were performed between December 2005 and August 2007. Ten patients required HPCS using a vein graft all survived without small-for-size syndrome (SFSS) and shunt complications with a median follow-up of 296 days. One patient without HPCS died of chronic vascular rejection. In all cases, PVP were regulated successfully under 20 mmHg by HPCS. Graft volume reached in mean 84.3% of standard liver volume in right lobe grafts and mean 95.4% in left lobe grafts at 3 months after liver transplantation. Actuarial rate of shunt patency at 1, 3, 6 months and 1 year were 80%, 55%, 26% and 20%, respectively. Selective HPCS based on PVP is an effective procedure and results in excellent patient and graft survival with avoidance of SFSS in grafts greater than 0.6% of GRWR.

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Year:  2008        PMID: 18261170     DOI: 10.1111/j.1600-6143.2007.02144.x

Source DB:  PubMed          Journal:  Am J Transplant        ISSN: 1600-6135            Impact factor:   8.086


  27 in total

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Review 3.  Portosystemic Shunts for "Too Small-for-Size Syndrome" After Liver Transplantation: A Systematic Review.

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Journal:  J Gastrointest Surg       Date:  2018-09-27       Impact factor: 3.452

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Journal:  Surg Today       Date:  2014-06-05       Impact factor: 2.549

6.  Small for size syndrome following living donor and split liver transplantation.

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8.  Portal modulation effects of terlipressin on liver regeneration and survival in a porcine model subjected to 90% hepatectomy.

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Journal:  Am J Transl Res       Date:  2021-06-15       Impact factor: 4.060

9.  Matrix metalloproteinase-9 in the initial injury after hepatectomy in mice.

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Journal:  World J Gastroenterol       Date:  2013-05-28       Impact factor: 5.742

10.  Portal inflow preservation during portal diversion in small-for-size syndrome.

Authors:  Xian-Qiang Wang; Yue-Fang Xu; Jing-Wang Tan; Wen-Ping Lv; Zhe Liu; Jian-Ping Zeng; Jia-Hong Dong
Journal:  World J Gastroenterol       Date:  2014-01-28       Impact factor: 5.742

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