| Literature DB >> 18260672 |
Christophe Blaszykowski1, Evangelos Aktoudianakis, Dino Alberico, Cyril Bressy, David G Hulcoop, Farnaz Jafarpour, Arash Joushaghani, Benoît Laleu, Mark Lautens.
Abstract
A norbornene-mediated palladium-catalyzed sequence is described in which an alkyl-aryl bond and an aryl-heteroaryl bond are formed in one reaction vessel. The aryl-heteroaryl bond-forming step occurs via a direct arylation reaction. A number of six-, seven-, and eight-membered ring-annulated indoles, pyrroles, pyrazoles, and azaindoles were synthesized from the corresponding bromoalkyl azole and an aryl iodide.Entities:
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Year: 2008 PMID： 18260672 DOI： 10.1021/jo702052b
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354