Literature DB >> 18257605

Pharmacological therapy for female sexual dysfunction: has progress been made?

Susan R Davis1, Esme A Nijland.   

Abstract

The investigation of female sexual dysfunction (FSD) is an evolving area in which definitions and models for female sexual functioning are being continually reviewed and revised. The lack of consensus amongst experts in the field and regulating authorities regarding appropriate inclusion and exclusion criteria for FSD trials, and main outcome measures appropriate for the evaluation of drug interventions has somewhat hampered progression in this area. Nonetheless, there is evidence from randomized controlled trials that androgen therapy improves the quality of the sexual experience for postmenopausal women with low libido, and preliminary data that this may also apply to premenopausal women.

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Year:  2008        PMID: 18257605     DOI: 10.2165/00003495-200868030-00001

Source DB:  PubMed          Journal:  Drugs        ISSN: 0012-6667            Impact factor:   9.546


  29 in total

Review 1.  Pharmacological effects on sexual function.

Authors:  J Chris Carey
Journal:  Obstet Gynecol Clin North Am       Date:  2006-12       Impact factor: 2.844

2.  Efficacy and safety of a testosterone patch for the treatment of hypoactive sexual desire disorder in surgically menopausal women: a randomized, placebo-controlled trial.

Authors:  Susan R Davis; M J van der Mooren; Rik H W van Lunsen; Patrice Lopes; Claude Ribot; Jean Ribot; Margaret Rees; Alain Moufarege; Cynthia Rodenberg; Akshay Buch; David W Purdie
Journal:  Menopause       Date:  2006 May-Jun       Impact factor: 2.953

3.  Long-term consequences of polycystic ovary syndrome: results of a 31 year follow-up study.

Authors:  Sarah Wild; Tracey Pierpoint; Howard Jacobs; Paul McKeigue
Journal:  Hum Fertil (Camb)       Date:  2000       Impact factor: 2.767

4.  Testosterone patch for low sexual desire in surgically menopausal women: a randomized trial.

Authors:  John E Buster; Sheryl A Kingsberg; Oscar Aguirre; Candace Brown; Jeffrey G Breaux; Akshay Buch; Cynthia A Rodenberg; Kathryn Wekselman; Peter Casson
Journal:  Obstet Gynecol       Date:  2005-05       Impact factor: 7.661

Review 5.  Tibolone: a steroid with a tissue-specific mode of action.

Authors:  H J Kloosterboer
Journal:  J Steroid Biochem Mol Biol       Date:  2001 Jan-Mar       Impact factor: 4.292

6.  Sexual dysfunction in the United States: prevalence and predictors.

Authors:  E O Laumann; A Paik; R C Rosen
Journal:  JAMA       Date:  1999-02-10       Impact factor: 56.272

7.  Changes in clitoral blood flow in premenopausal women affected by type 1 diabetes after single 100-mg administration of sildenafil.

Authors:  Salvatore Caruso; Salvatore Rugolo; Daniela Mirabella; Giorgia Intelisano; Lucia Di Mari; Antonio Cianci
Journal:  Urology       Date:  2006-07       Impact factor: 2.649

8.  Transdermal testosterone therapy improves well-being, mood, and sexual function in premenopausal women.

Authors:  Rebecca Goldstat; Esther Briganti; Jane Tran; Rory Wolfe; Susan R Davis
Journal:  Menopause       Date:  2003 Sep-Oct       Impact factor: 2.953

9.  Safety and efficacy of sildenafil citrate for the treatment of female sexual arousal disorder: a double-blind, placebo controlled study.

Authors:  Jennifer R Berman; Laura A Berman; Steven M Toler; Jennifer Gill; Scott Haughie
Journal:  J Urol       Date:  2003-12       Impact factor: 7.450

10.  Tibolone and transdermal E2/NETA for the treatment of female sexual dysfunction in naturally menopausal women: results of a randomized active-controlled trial.

Authors:  Esme A Nijland; Willibrord C M Weijmar Schultz; Jörgen Nathorst-Boös; Frans A Helmond; Rik H W Van Lunsen; Santiago Palacios; Robert J Norman; Roel J Mulder; Susan R Davis
Journal:  J Sex Med       Date:  2008-03       Impact factor: 3.802

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  2 in total

1.  Management of hypoactive sexual desire disorder in women: current and emerging therapies.

Authors:  Rossella E Nappi; Ellis Martini; Erica Terreno; Francesca Albani; Valentina Santamaria; Silvia Tonani; Luca Chiovato; Franco Polatti
Journal:  Int J Womens Health       Date:  2010-08-09

2.  Role of hormones in hypoactive sexual desire disorder and current treatment.

Authors:  Ahmed AlAwlaqi; Houda Amor; Mohamed E Hammadeh
Journal:  J Turk Ger Gynecol Assoc       Date:  2017-12-15
  2 in total

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