Literature DB >> 18256795

How I treat status epilepticus in the Neuro-ICU.

Panayiotis N Varelas1.   

Abstract

Status epilepticus still remains a formidable adversary to neurointensivists. Although the majority of cases admitted to the Neuro-ICU are easily controlled with one or two antiepileptic drug defense lines, several cases become refractory and end up receiving general anesthetics for days or weeks with significant morbidity. Treatment algorithms have been published and should be followed, but in many cases they are inadequate because, especially in the distal branches of the treatment tree, are based on anecdotal data or small series of patients. In addition, a double-blind, randomized-controlled study in status has not been done for many years and solid data are lacking for the newer antiepileptics. Therefore, in the moderately to severely refractory cases, status treatment is based on personal previous experience and becomes an art more than a science. In this review of a difficult case, we discuss some fine details of the treatment provided and emphasize the multidisciplinary approach that should be followed including involvement of neurointensivists, epileptologists, electroencephalographers, and neurosurgeons.

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Year:  2008        PMID: 18256795     DOI: 10.1007/s12028-008-9052-4

Source DB:  PubMed          Journal:  Neurocrit Care        ISSN: 1541-6933            Impact factor:   3.210


  24 in total

Review 1.  The use of topiramate in refractory status epilepticus.

Authors:  A R Towne; L K Garnett; E J Waterhouse; L D Morton; R J DeLorenzo
Journal:  Neurology       Date:  2003-01-28       Impact factor: 9.910

Review 2.  The management of refractory status epilepticus: an update.

Authors:  Daniel H Lowenstein
Journal:  Epilepsia       Date:  2006       Impact factor: 5.864

Review 3.  Management of seizures in the critically ill.

Authors:  Panayiotis N Varelas; Marianna Spanaki
Journal:  Neurologist       Date:  2006-05       Impact factor: 1.398

4.  Intravenous valproate as an innovative therapy in seizure emergency situations including status epilepticus--experience in 102 adult patients.

Authors:  Christian N A Peters; Bernd Pohlmann-Eden
Journal:  Seizure       Date:  2005-04       Impact factor: 3.184

5.  Neurosurgical treatment of status epilepticus.

Authors:  Yu-Tze Ng; John F Kerrigan; Harold L Rekate
Journal:  J Neurosurg       Date:  2006-11       Impact factor: 5.115

6.  A prospective, randomized study comparing intramuscular midazolam with intravenous diazepam for the treatment of seizures in children.

Authors:  J M Chamberlain; M A Altieri; C Futterman; G M Young; D W Ochsenschlager; Y Waisman
Journal:  Pediatr Emerg Care       Date:  1997-04       Impact factor: 1.454

7.  Relapse and survival after barbiturate anesthetic treatment of refractory status epilepticus.

Authors:  K B Krishnamurthy; F W Drislane
Journal:  Epilepsia       Date:  1996-09       Impact factor: 5.864

8.  Status epilepticus at an urban public hospital in the 1980s.

Authors:  D H Lowenstein; B K Alldredge
Journal:  Neurology       Date:  1993-03       Impact factor: 9.910

9.  Treatment of status epilepticus: a survey of neurologists.

Authors:  Jan Claassen; Lawrence J Hirsch; Stephan A Mayer
Journal:  J Neurol Sci       Date:  2003-07-15       Impact factor: 3.181

10.  Determinants of mortality in status epilepticus.

Authors:  A R Towne; J M Pellock; D Ko; R J DeLorenzo
Journal:  Epilepsia       Date:  1994 Jan-Feb       Impact factor: 5.864

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  3 in total

1.  Status epilepticus.

Authors:  Panayiotis N Varelas; Marek A Mirski
Journal:  Curr Neurol Neurosci Rep       Date:  2009-11       Impact factor: 5.081

2.  Management of status epilepticus in neurological versus medical intensive care unit: does it matter?

Authors:  Panayiotis N Varelas; Jesse Corry; Mohammed Rehman; Tamer Abdelhak; Lonni Schultz; Marianna Spanaki; James Bartscher
Journal:  Neurocrit Care       Date:  2013-08       Impact factor: 3.210

Review 3.  Super-Refractory Status Epilepticus.

Authors:  Mauricio Ruiz Cuero; Panayiotis N Varelas
Journal:  Curr Neurol Neurosci Rep       Date:  2015-11       Impact factor: 5.081

  3 in total

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