Literature DB >> 18256770

Cultures of hESM human embryonic stem cells: chromosomal aberrations and karyotype stability.

M A Prokhorovich1, M A Lagar'kova, A G Shilov, T V Karamysheva, S L Kiselyov, N B Rubtsov.   

Abstract

Cytogenetic analysis of karyotypes of hESM01-hESM04 human embryonic stem cells and substrains derived from these strains showed that all these strains retained normal karyotype during long-term culturing. Two substrains of embryonic stem cells with chromosome aberrations indicating clonal origin of these strains were detected. The potentialities of using analysis of chromosome variability of embryonic stem cells for evaluation of predisposition of the corresponding genotypes to the formation of chromosome abnormalities are discussed.

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Mesh：

Year:  2007        PMID： 18256770     DOI： 10.1007/s10517-007-0271-z

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  5 in total

1.  High resolution array-CGH characterization of human stem cells using a stem cell focused microarray.

Authors:  Aaron M Elliott; Kristi A Hohenstein Elliott; Anja Kammesheidt
Journal:  Mol Biotechnol       Date:  2010-11       Impact factor: 2.695

2.  Allele-Specific Biased Expression of the CNTN6 Gene in iPS Cell-Derived Neurons from a Patient with Intellectual Disability and 3p26.3 Microduplication Involving the CNTN6 Gene.

Authors:  Maria M Gridina; Natalia M Matveeva; Veniamin S Fishman; Aleksei G Menzorov; Helen A Kizilova; Nikolay A Beregovoy; Igor I Kovrigin; Inna E Pristyazhnyuk; Igor P Oscorbin; Maxim L Filipenko; Anna A Kashevarova; Nikolay A Skryabin; Tatyana V Nikitina; Elena A Sazhenova; Ludmila P Nazarenko; Igor N Lebedev; Oleg L Serov
Journal:  Mol Neurobiol       Date:  2018-01-11       Impact factor: 5.590

3.  Human embryonic stem cell lines isolation, cultivation, and characterization.

Authors:  Maria A Lagarkova; Artem V Eremeev; Anatoly V Svetlakov; Nikolay B Rubtsov; Sergei L Kiselev
Journal:  In Vitro Cell Dev Biol Anim       Date:  2010-02-23       Impact factor: 2.416

4.  Error-prone nonhomologous end joining repair operates in human pluripotent stem cells during late G2.

Authors:  Alexandra N Bogomazova; Maria A Lagarkova; Leyla V Tskhovrebova; Maria V Shutova; Sergey L Kiselev
Journal:  Aging (Albany NY)       Date:  2011-06       Impact factor: 5.682

Review 5.  Insight and Recent Advances into the Role of Topography on the Cell Differentiation and Proliferation on Biopolymeric Surfaces.

Authors:  Raluca Tudureanu; Iuliana M Handrea-Dragan; Sanda Boca; Ioan Botiz
Journal:  Int J Mol Sci       Date:  2022-07-13       Impact factor: 6.208
  5 in total

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